Journal article
Effects of Diazepam on Hippocampal Excitability in the Rat: Action in the Dentate Area
Abstract
Acute and chronic experiments were performed on rats to examine the effects of diazepam (Valium) on recurrent inhibition in the monosynaptic perforant path-dentate synapse of the dentate area of the dorsal hippocampus. Evidence was obtained which indicated that diazepam facilitated a presumably GABA mediated post synaptic recurrent inhibition in both acute and chronic preparations at 1 and 2 mg/kg doses (IP). Acute studies also revealed that …
Authors
Adamec RE; McNaughton B; Racine R; Livingston KE
Journal
Epilepsia, Vol. 22, No. 2, pp. 205–215
Publisher
Wiley
Publication Date
April 1981
DOI
10.1111/j.1528-1157.1981.tb04103.x
ISSN
0013-9580