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Development of spontaneous seizures over extended...
Journal article

Development of spontaneous seizures over extended electrical kindling. II. Persistence of dentate inhibitory suppression

Abstract

The effect of an extended program of perforant path or amygdala kindling on paired-pulse suppression in the dentate gyrus was studied in male hooded rats. Repeated kindling stimulations were delivered twice or three times daily until either 300 stimuli had been delivered or generalized convulsions had been observed to occur spontaneously. Paired-pulse suppression was monitored prior to and over the course of kindling using a standard variable …

Authors

Milgram NW; Michael M; Cammisuli S; Head E; Ferbinteanu J; Reid C; Murphy MP; Racine R

Journal

Brain Research, Vol. 670, No. 1, pp. 112–120

Publisher

Elsevier

Publication Date

January 1995

DOI

10.1016/0006-8993(94)01277-o

ISSN

0006-8993