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Separation of human plasma proteins HSA and HIgG...
Journal article

Separation of human plasma proteins HSA and HIgG using high-capacity macroporous gel-filled membranes

Abstract

This paper discusses the separation of human serum albumin (HSA), the most abundant protein present in plasma from human immunoglobulin G (HIgG) by membrane chromatography using a novel macroporous gel-filled membrane (designated Q Type 2). The membrane was prepared by anchoring a quaternary ammonium salt macroporous gel within the pores of a non-woven, polypropylene fabric. Factors affecting HSA binding were examined and operating conditions …

Authors

Kanani DM; Komkova E; Wong T; Mika A; Childs RF; Ghosh R

Journal

Biochemical Engineering Journal, Vol. 35, No. 3, pp. 295–300

Publisher

Elsevier

Publication Date

8 2007

DOI

10.1016/j.bej.2007.01.034

ISSN

1369-703X