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Label-Free DNA Biosensors Based on Functionalized...
Journal article

Label-Free DNA Biosensors Based on Functionalized Carbon Nanotube Field Effect Transistors

Abstract

A carbon nanotube transistor array was used to detect DNA hybridization. A new approach to ensure specific adsorption of DNA to the nanotubes was developed. The polymer poly (methylmethacrylate(0.6)-co-poly(ethyleneglycol)methacrylate(0.15)-co-N-succinimidyl methacrylate(0.25)) was synthesized and bonded noncovalently to the nanotube. Aminated single-strand DNA was then attached covalently to the polymer. After hybridization, statistically …

Authors

Martínez MT; Tseng Y-C; Ormategui N; Loinaz I; Eritja R; Bokor J

Journal

Nano Letters, Vol. 9, No. 2, pp. 530–536

Publisher

American Chemical Society (ACS)

Publication Date

February 11, 2009

DOI

10.1021/nl8025604

ISSN

1530-6984