Journal article
Biaryl Ketones by Suzuki–Miyaura Cross‐Coupling of Organotrifluoroborates and Acyl Chlorides
Abstract
A procedure for the synthesis of biaryl ketones by a palladium‐catalyzed Suzuki–Miyaura cross‐coupling reaction between phenyltrifluoroborates and benzoyl chlorides is described. Organotrifluoroborates are unique to other cross‐coupling reagents as they have a high functional‐group tolerance and are moisture‐stable. Moderate to excellent yields were obtained for all substrates tested.
Authors
Forbes AM; Meier GP; Jones‐Mensah E; Magolan J
Journal
European Journal of Organic Chemistry, Vol. 2016, No. 17, pp. 2983–2987
Publisher
Wiley
Publication Date
6 2016
DOI
10.1002/ejoc.201600199
ISSN
1434-193X