Biaryl Ketones by Suzuki–Miyaura Cross‐Coupling of Organotrifluoroborates and Acyl Chlorides Journal Articles uri icon

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  • A procedure for the synthesis of biaryl ketones by a palladium‐catalyzed Suzuki–Miyaura cross‐coupling reaction between phenyltrifluoroborates and benzoyl chlorides is described. Organotrifluoroborates are unique to other cross‐coupling reagents as they have a high functional‐group tolerance and are moisture‐stable. Moderate to excellent yields were obtained for all substrates tested.


  • Forbes, Alaina M
  • Meier, G Patrick
  • Jones‐Mensah, Ebenezer
  • Magolan, Jakob

publication date

  • June 2016