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Journal article

Protonation of Tetraphenyl‐ and 2,3,4‐Triphenylcyclopentadienone – An NMR and X‐ray Crystallographic Study

Abstract

The protonation of 2,3,4,5‐tetraphenylcyclopentadienone (tetracyclone) yields 6,11‐diphenyl‐5 H ‐benzo[ a ]fluoren‐5‐one ( 17 ) and 2,3,4,5‐tetraphenylcyclopent‐2‐en‐1‐one ( 18 ) as the major products. This contrasts with the pyrolysis of tetracyclone, which yields 5,6‐diphenyl‐11 H ‐benzo[ a ]fluoren‐11‐one ( 22 ), a structural isomer of 17 . Mechanisms are presented that rationalize these observations. The protonation of 4‐hydroxy‐2,3,4‐triphenylcyclopent‐2‐en‐1‐none, the precursor to 2,3,4‐triphenylcyclopentadienone, generates 2‐(2′‐oxo‐3′,4′,5′‐triphenylcyclopent‐3′‐enyl)‐3,4,5‐triphenylcyclopenta‐2,4‐dienone ( 30 ), which has been unequivocally characterized by X‐ray crystallography. The establishment of the conformation of molecule 30 in the solid state, which correlates with the conformation in solution, provides a rationale for the subsequent formation of the tetrahydro‐pentaphenyl‐ as ‐indacene‐3,4‐dione ( 32 ) upon further protonation.

Authors

Harrington LE; Britten JF; Casey M; Grealis J; Ortin Y; Müller‐Bunz H; McGlinchey MJ

Journal

European Journal of Organic Chemistry, Vol. 2017, No. 22, pp. 3249–3255

Publisher

Wiley

Publication Date

June 16, 2017

DOI

10.1002/ejoc.201700019

ISSN

1434-193X

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