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Field trial of oral cholera vaccines in...
Journal article

Field trial of oral cholera vaccines in Bangladesh: results from three-year follow-up

Abstract

The protective efficacy (PE) of B subunit killed whole-cell (BS-WC) and killed whole-cell-only (WC) oral cholera vaccines was assessed in a randomised double-blind field trial among children aged 2-15 years and women over 15 years in rural Bangladesh. Among the 62 285 subjects who received three doses of BS-WC, WC, or Escherichia coli K12 strain placebo, cumulative PE at 3 years of follow-up was 50% for BS-WC and 52% for WC. PE was similar …

Authors

Clemens JD; Sack DA; Harris JR; van Loon F; Chakraborty J; Ahmed F; Rao MR; Khan MR; Yunus; Huda N

Journal

The Lancet, Vol. 335, No. 8684, pp. 270–273

Publisher

Elsevier

Publication Date

2 1990

DOI

10.1016/0140-6736(90)90080-o

ISSN

0140-6736