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Effect of induced metabolic acidosis on human...
Journal article

Effect of induced metabolic acidosis on human skeletal muscle metabolism during exercise

Abstract

The roles of pyruvate dehydrogenase (PDH), glycogen phosphorylase (Phos), and their regulators in lactate (Lac) metabolism were examined during incremental exercise after ingestion of 0.3 g/kg of either NH4Cl [metabolic acidosis (ACID)] or CaCO3[control (CON)]. Subjects were studied at rest, at rest postingestion, and during continuous steady-state cycling at three stages (15 min each): 30, 60, and 75% of maximal oxygen uptake. Radial artery …

Authors

Hollidge-Horvat MG; Parolin ML; Wong D; Jones NL; Heigenhauser GJF

Journal

American Journal of Physiology-Endocrinology and Metabolism, Vol. 277, No. 4, pp. E647–E658

Publisher

American Physiological Society

Publication Date

October 1, 1999

DOI

10.1152/ajpendo.1999.277.4.e647

ISSN

0193-1849