New Standards in Antithrombotic Therapy: Concepts, Clinical Evidence, and Applications

Venous thromboembolism (VTE) is a significant medical disorder. It can present as either silent or symptomatic deep venous thrombosis (DVT) or pulmonary embolism (PE). Approximately 200,000 new VTE events occur each year in the United States, and the incidence is expected to increase with the ``graying'' of America. Unfortunately, the initial presentation may be sudden death from a PE. Even among patients whose PE is heralded by symptoms, …