Journal article
The effects of lithium on muscle contractile function in humans
Abstract
A side effect of lithium (Li+) treatment is fatigue. Li+ decreases inositol triphosphate (IP3) accumulation and IP3 may play a role in excitation-contraction (E-C) coupling in skeletal muscle. Li+ carbonate (600 mg b.i.d. x 6 days) was administered in a randomized, double-blind fashion to 12 males to measure the effect upon muscle contractile function: peak twitch torque (PTT), time to PTT, half-relaxation time, maximal voluntary contraction …
Authors
Tarnopolsky MA; Hicks A; Winegard K
Journal
Muscle & Nerve, Vol. 19, No. 3, pp. 311–318
Publisher
Wiley
Publication Date
March 1996
DOI
10.1002/(sici)1097-4598(199603)19:3<311::aid-mus5>3.0.co;2-g
ISSN
0148-639X