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Tricarboxylic acid cycle intermediates in human...
Journal article

Tricarboxylic acid cycle intermediates in human muscle at rest and during prolonged cycling

Abstract

Previous studies have used the muscle concentration of citrate + malate + fumarate to estimate tricarboxylic acid (TCA) cycle pool size in humans [e.g., Am. J. Physiol. 259 (Cell Physiol. 28): C834-C841, 1990]. Our purpose was to quantify changes in individual TCA cycle intermediates (TCAI) and total pool size by measuring the concentrations of the eight TCAI in human muscle. Eight males cycled to exhaustion (Exh) at approximately 70% of their …

Authors

Gibala MJ; Tarnopolsky MA; Graham TE

Journal

American Journal of Physiology, Vol. 272, No. 2, pp. e239–e244

Publisher

American Physiological Society

Publication Date

February 1, 1997

DOI

10.1152/ajpendo.1997.272.2.e239

ISSN

0002-9513