Journal article
Chronic hypoxic hypercapnia modifies in vivo and in vitro ventilatory chemoreflexes in the cane toad
Abstract
Previous studies have shown that exposure to chronic hypoxia (CH) and chronic hypercapnia (CHC) alone have opposite effects on central respiratory-related pH/CO(2) chemosensitivity in the cane toad (Bufo marinus). This study examined the effects of chronic hypoxic hypercapnia (CHH) on central pH/CO(2) chemosensitivity. Cane toads were maintained at 10% O(2) and 3.5% CO(2) for 10 days. Changes in central pH/CO(2)-sensitive fictive breathing were …
Authors
Srivaratharajah K; Cui A; McAneney J; Reid SG
Journal
Respiratory Physiology & Neurobiology, Vol. 160, No. 3, pp. 249–258
Publisher
Elsevier
Publication Date
February 2008
DOI
10.1016/j.resp.2007.10.007
ISSN
1569-9048