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The role of the guanine insertion enzyme in...
Journal article

The role of the guanine insertion enzyme in Q-biosynthesis in Drosophila melanogaster

Abstract

Drosophila tRNA can be guanylated by a crude enzyme from rabbit reticulocytes. Guanylating activity is also present in crude extracts of adult Drosophila. A major product of this reaction as well as several minor ones were resolved by RPC-5 chromatography. The main substrate of both the Drosophila and rabbit reticulocyte enzymes was the non-Q-containing aspartic acid tRNA, tRNA2gammaAsp. The QU-lacking (gamma) forms of asparagine, histidine and …

Authors

McKinnon RD; Wosnick MA; White BN

Journal

Nucleic Acids Research, Vol. 5, No. 12, pp. 4865–4876

Publisher

Oxford University Press (OUP)

Publication Date

1978

DOI

10.1093/nar/5.12.4865

ISSN

0305-1048