Journal article
Carrier detection strategy in haemophilia A: the benefits of combined DNA marker analysis and coagulation testing in sporadic haemophilic families.
Abstract
A province wide study of carrier detection methods in haemophilia A is reported. The principal objective of this project was to compare the relative merits of coagulation testing and DNA marker analysis in carrier diagnosis for a large unselected haemophilic population. Factor VIII:C (F.VIII:C) and von Willebrand factor antigen (vWf:Ag) were measured on plasma samples sent to a central laboratory. Coagulation results were analysed by a logistic …
Authors
Lillicrap D; Holden JJ; Giles AR; White BN
Journal
British Journal of Haematology, Vol. 70, No. 3, pp. 321–326
Publisher
Wiley
Publication Date
11 1988
DOI
10.1111/j.1365-2141.1988.tb02489.x
ISSN
0007-1048