Journal article
Trinucleotide repeat expansion in the FRAXE locus is not common among institutionalized individuals with non‐specific developmental disabilities
Abstract
Expansion of a polymorphic GCC-repeat at the FRAXE locus has been associated with expression of chromosome fragility at this site and cognitive impairment in some individuals previously testing negative for CGG-repeat expansion in the fragile X mental retardation-1 (FMR1) gene. To determine the frequency of FRAXE triplet repeat expansion among persons with developmental disability, 396 individuals from two institutions were studied, all of whom …
Authors
Holden JJA; Julien‐Inalsingh C; Chalifoux M; Wing M; Scott E; Fidler K; Swift I; Maidment B; Knight SJL; Davies KE
Journal
American Journal of Medical Genetics, Vol. 64, No. 2, pp. 420–423
Publisher
Wiley
Publication Date
August 9, 1996
DOI
10.1002/(sici)1096-8628(19960809)64:2<420::aid-ajmg37>3.0.co;2-f
ISSN
0148-7299