Gender Differences in Severity and Correlates of Depression Symptoms in People Living with HIV in Ontario, Canada Academic Article uri icon

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  • This study investigates the differences in severity and correlates of depression symptoms among 1069 men and 267 women living with HIV in Ontario, Canada, who completed the 20-item Center for Epidemiologic Studies Depression Scale (CES-D). Women had higher CES-D scores than that of men (median [interquartile range]: 13 [5-26] versus 9 [3-20], P=.0004). More women had total CES-D scores>15 (mild-moderate depression; 44% versus 33%, P=.002) and >21 (severe depression; 31% versus 23%, P=.003). Unlike men, at age 40, women's scores increased yearly (0.4 per increased year, P=.005). The distribution of scores differed by gender: There was no difference in the 10th percentile of depression scores, 0 (95% confidence interval [CI]: 1.0-1.0) but the 75th percentile of depression scores for women was 6 (95% CI: 2.0-10.0) points higher than that of men. Important gender differences exist in depression symptoms and in correlates of symptoms in people living with HIV.


  • Aljassem, Kinda
  • Raboud, Janet M
  • Hart, Trevor A
  • Benoit, Anita
  • Su, DeSheng
  • Margolese, Shari L
  • Rourke, Sean B
  • Rueda, Sergio
  • Burchell, Ann
  • Cairney, John
  • Shuper, Paul
  • Loutfy, Mona R

publication date

  • January 2016