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In vivo skeletal imaging of 18F-fluoride with...
Journal article

In vivo skeletal imaging of 18F-fluoride with positron emission tomography reveals damage- and time-dependent responses to fatigue loading in the rat ulna

Abstract

The skeletal response to damaging fatigue loading is not fully understood. We used (18)F-fluoride PET to describe the time course of the skeletal response following the creation of increasing levels of in vivo, fatigue-induced damage. The right forelimbs of 40 adult rats were loaded in vivo in cyclic compression to four levels of subfracture, fatigue displacement: 30, 45, 65, or 85% of fracture displacement. Rats were injected with a …

Authors

Silva MJ; Uthgenannt BA; Rutlin JR; Wohl GR; Lewis JS; Welch MJ

Journal

Bone, Vol. 39, No. 2, pp. 229–236

Publisher

Elsevier

Publication Date

August 2006

DOI

10.1016/j.bone.2006.01.149

ISSN

8756-3282