Jeffrey Pernica
Associate Professor, Pediatrics

Dr. Jeffrey Pernica, MSc MD FRCPC DTMH, is the Head of the Division of Infectious Disease and Associate Professor in the Department of Pediatrics at McMaster University. His clinical interests, aside from infectious disease in general, include tropical medicine (he is a member of the Canadian Committee to Advise on Tropical Medicine and Travel), immunization (he is the director of the Special Immunization Clinic at McMaster Children’s Hospital), and congenital CMV (he is the regional lead for the Ontario CMV newborn screening program).

His research interests relate to the optimization of the diagnosis and treatment of respiratory infections, enteric infections, and sepsis, both for children living in resource-rich as well as resource-limited settings. He has long been involved in global child health and global health research, having worked on retrospective cohort studies, prospective cohort studies, and randomized trials in Botswana and other low- and middle-income countries.

He was the recipient of a Hamilton Health Sciences Early Career Award and an IDWeek 2020 Investigator Award. He has received research funding as PI from Hamilton Health Sciences, the Physicians’ Services Incorporated Foundation, the Hamilton Academic Health Sciences Organization Innovation Fund, and Grand Challenges Canada.
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Scholarly Activity in McMaster Experts
 
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selected scholarly activity

  • academic article

    • Assessment of nasopharyngeal Streptococcus pneumoniae colonization does not permit discrimination between Canadian children with viral and bacterial respiratory infection: a matched-cohort cross-sectional study.  BMC Infectious Diseases.  21:509. 2021
    • Epidemiology, clinical features and outcomes of incident tuberculosis in children in Canada in 2013–2016: results of a national surveillance study.  Archives of Disease in Childhood.  archdischild-2021-322092. 2021
    • Single-centre, open-label, randomised, trial to compare rapid molecular point-of-care streptococcal testing to standard laboratory-based testing for the management of streptococcal pharyngitis in children: study protocol.  BMJ Open.  11:e047271-e047271. 2021
    • Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia.  Archives of Pediatrics and Adolescent Medicine.  175:475-475. 2021
    • Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected Nasopharyngeal Swabs for COVID-19 Diagnosis in Outpatients.  Journal of Clinical Microbiology.  59. 2021
    • Risk of latent and active tuberculosis infection in travellers: a systematic review and meta-analysis.  Journal of Travel Medicine.  28. 2021
    • Waning Vaccine Immunity and Vaccination Responses in Children Treated for Acute Lymphoblastic Leukemia: A Canadian Immunization Research Network Study.  Clinical Infectious Diseases.  71:e439-e448. 2020
    • Global molecular diversity of RSV – the “INFORM RSV” study.  BMC Infectious Diseases.  20:450. 2020
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    • Paediatric critical illness associated with respiratory infection: a single-centre, retrospective cohort study.  BMJ Paediatrics Open.  4:e000640-e000640. 2020
    • Evaluation of Anatomically Designed Flocked Rectal Swabs for Use with the BioFire FilmArray Gastrointestinal Panel for Detection of Enteric Pathogens in Children Admitted to Hospital with Severe Gastroenteritis.  Journal of Clinical Microbiology.  57. 2019
    • Diversity of Rotavirus Strains Circulating in Botswana before and after introduction of the Monovalent Rotavirus Vaccine.  Vaccine.  37:6324-6328. 2019
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    • New Tools to Test Stool.  Infectious Disease Clinics of North America.  33:197-212. 2019
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    • Identification and management of Shigella infection in children with diarrhoea: a systematic review and meta-analysis.  The Lancet Global Health.  5:e1235-e1248. 2017
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    • Immunizing Patients with Adverse Events Following Immunization in the Canadian Special Immunization Clinic Network (2015–2017).  Open Forum Infectious Diseases.  4:S515-S516. 2017
    • Rapid enteric testing to permit targeted antimicrobial therapy, with and without Lactobacillus reuteri probiotics, for paediatric acute diarrhoeal disease in Botswana: A pilot, randomized, factorial, controlled trial.  PLoS ONE.  12:e0185177-e0185177. 2017
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    • Correlation of Clinical Outcomes With Multiplex Molecular Testing of Stool From Children Admitted to Hospital With Gastroenteritis in Botswana.  Journal of the Pediatric Infectious Diseases Society.  5:312-318. 2016
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