selected scholarly activity
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conferences
- RNA-seq transcriptome analysis of human allergen-specific T cells suggests a role for IL-8 downregulation and modulation of allergic inflammatory cells as one of several potential mechanisms of action of intradermal immunotherapy with Fel d 1 synthetic peptides. Allergy. European Journal of Allergy and Clinical Immunology. 4-4. 2016
- Mapping the local inflammatory cytokine secretion following a cumulative allergen dose using the Allergic Rhinitis Clinical Investigator Collaborative Nasal Allergen Challenge model. Allergy. European Journal of Allergy and Clinical Immunology. 440-440. 2015
- Whole blood immune transcriptome profiling reveals systemic pathways associated with the mechanism of action of cat-synthetic peptide immunoregulatory epitopes. Allergy. European Journal of Allergy and Clinical Immunology. 632-632. 2015
- Multiple Cumulative Allergen Concentration Delivery for Nasal Allergen Challenge – a Refinement of the Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC) Protocol. Journal of Allergy and Clinical Immunology. AB58-AB58. 2015
- The Nasal Allergen Challenge Protocol of the Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC): Validation in a Clinical Trial of Cat Synthetic Peptide Immunoregulatory Epitopes (Cat-SPIRE). Journal of Allergy and Clinical Immunology. AB142-AB142. 2015
- Thymic Stromal Lymphopoietin Secretion As a Function of Genotype. Journal of Allergy and Clinical Immunology. AB152-AB152. 2015
- Effect Of Allergen Challenge On Inflammation Induced By Toll-Like Receptor Stimulation In A Nasal Challenge Model. American Journal of Respiratory and Critical Care Medicine. 2015
- Natural T Regulatory Cells In Healthy And Asthmatic Subjects - Frequency And Function Are Phenotype-Dependent. American Journal of Respiratory and Critical Care Medicine. 2015
- THE ALLERGIC RHINITIS CLINICAL INVESTIGATOR COLLABORATIVE-CYTOKINE PROFILING OF SYNTHETIC ABSORPTIVE MATRIX ELUATES TO OPTIMIZE A STANDARD NASAL ALLERGEN CHALLENGE PROTOCOL. Annals of Allergy, Asthma and Immunology. A20-A20. 2013
- The Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC) – a Multicentre Pilot Study to Optimize a Standard Nasal Allergen Challenge Protocol. Journal of Allergy and Clinical Immunology. AB135-AB135. 2013
- The Allergic Rhinitis Clinical Investigator Collaborative (ar-Cic) - Optimization Of Screening Nasal Allergen Challenge For Use In Clinical Trials. American Journal of Respiratory and Critical Care Medicine. 2013
- Baseline survey of practice in diagnosis and staging of carcinoma of the bronchus. Thorax. 19-19. 2004
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journal articles
- Effect of Gender on Feedback Associated with a Direct Clinical Observation Tool Used during Clerkship at McMaster University. Journal of General Internal Medicine. 2021
- Chronic Eosinophilic Pneumonia: A Diagnostic Challenge. Journal of Allergy and Clinical Immunology: In Practice. 5:1737-1738. 2017
- Administering multiple cumulative allergen challenges. Annals of Allergy, Asthma and Immunology. 117:326-328. 2016
- The Allergic Rhinitis – Clinical Investigator Collaborative (AR-CIC): nasal allergen challenge protocol optimization for studying AR pathophysiology and evaluating novel therapies. Allergy, Asthma and Clinical Immunology. 11:16. 2015
- Thymic stromal lymphopoietin (TSLP) secretion from human nasal epithelium is a function of TSLP genotype. Mucosal Immunology. 8:993-999. 2015
- Relationship between Sputum Eosinophilia and Sinus Disease in Patients with Eosinophilic Bronchitis. American Journal of Rhinology & Allergy. 28:378-382. 2014
- T cell‐mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells. Clinical and Experimental Allergy. 44:953-964. 2014
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Safety and efficacy of an oral
CCR 3 antagonist in patients with asthma and eosinophilic bronchitis: a randomized, placebo‐controlled clinical trial. Clinical and Experimental Allergy. 44:508-516. 2014 - Amelioration of ovalbumin-induced allergic airway disease following Der p 1 peptide immunotherapy is not associated with induction of IL-35. Mucosal Immunology. 7:379-390. 2014
- Use of abatacept in eosinophilic asthma. Journal of Allergy and Clinical Immunology: In Practice. 2:220-221. 2014
- Mechanisms of Aspirin-Intolerant Asthma: Identifying Inflammatory Pathways in the Pathogenesis of Asthma. International Archives of Allergy and Immunology. 163:1-2. 2014
- Targeted therapy of bronchitis in obstructive airway diseases. Pharmacology and Therapeutics. 140:213-222. 2013
- Quantitative Sputum Cell Counts to Monitor Bronchitis: A Qualitative Study of Physician and Patient Perspectives. Canadian Respiratory Journal. 20:47-51. 2013
- Rapid Effect of Inhaled Ciclesonide in Asthma. Chest. 134:740-745. 2008
- Optimized Dialysis and Protease Inhibition of Sputum Dithiothreitol Supernatants. American Journal of Respiratory and Critical Care Medicine. 177:132-141. 2008
- The Effects of a Monoclonal Antibody Directed against Tumor Necrosis Factor-α in Asthma. American Journal of Respiratory and Critical Care Medicine. 174:753-762. 2006
- Glycopyrrolate Causes Prolonged Bronchoprotection and Bronchodilatation in Patients With Asthma. Chest. 128:1974-1979. 2005
- Nasal testing for novel anti‐inflammatory agents. Clinical and Experimental Allergy. 35:981-985. 2005
- Theophylline: Mechanism of action and use in asthma and chronic obstructive pulmonary disease. Drugs of Today. 40:55-55. 2004
- The contribution of histamine to the action of bradykinin in the human nasal airway. Immunopharmacology. 34:181-189. 1996