selected scholarly activity
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chapters
- Systemic vasculitis and the lung. 241-260. 2014
- Endoscopic Asthma Treatment. 529-534. 2013
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conferences
- Inhalational exposures in patients with fibrotic interstitial lung disease: Presentation, pulmonary function and survival in the Canadian Registry for Pulmonary Fibrosis.. Respirology. 635-644. 2022
- Malignancy Risk Associated With Mycophenolate Mofetil or Azathioprine in Patients With Fibrotic Interstitial Lung Disease. Chest. 1594-1597. 2022
- Association of BMI and Change in Weight With Mortality in Patients With Fibrotic Interstitial Lung Disease. Chest. 1320-1329. 2022
- Baseline characteristics and comorbidities in the CAnadian REgistry for Pulmonary Fibrosis. BMC Pulmonary Medicine. 223. 2019
- Pulmonary Manifestations in Microscopic Polyangiitis and Granulomatosis with Polyangiitis: A Multicenter Cohort Analysis. Arthritis & Rheumatology. 2017
- The Value Of A Systematic Assessment Of Medication Use And Polypharmacy In Patients With Ipf. American Journal of Respiratory and Critical Care Medicine. 2016
- 24: Lung cancer as an 'acute presentation' in acute unselected medical admissions at a district general hospital (audit at Kings Mill hospital, November 2013–May 2014). Lung Cancer. S9-S10. 2015
- P219 Evaluating medical thoracoscopy services at a District General Hospital over the past 13 years. Thorax. A175.1-A175. 2013
- Benefits Of Bronchial Thermoplasty Persist Out To 5 Years In Patients With Severe Asthma. American Journal of Respiratory and Critical Care Medicine. 2013
- PHYSIOTHERAPY RESOURCE NEEDS OF SEVERE RESPIRATORY FAILURE PATIENTS. Intensive Care Medicine. S91-S92. 2012
- 5-year Safety of Bronchial Thermoplasty Demonstrated in Patients with Moderate to Severe Asthma: Asthma Intervention Research (AIR) Trial. American Journal of Respiratory and Critical Care Medicine. 2010
- CAN WE IMPROVE ADJUVANT CHEMOTHERAPY UPTAKE IN THE MANAGEMENT OF RESECTED LUNG CANCER? AN AUDIT OF PRACTICE ACROSS THE MID TRENT LUNG CANCER NETWORK. Thorax. A144-A144. 2009
- AIR2 Trial: Execution of a Sham-Controlled Double-Blind Study of a Novel Device for the Treatment of Severe Asthma.. American Journal of Respiratory and Critical Care Medicine. 2009
- Air Filtration for Childhood Asthma: A Pilot Randomized Trial. American Journal of Respiratory and Critical Care Medicine. 2009
- Effect of Pharmacologic Agents on Ciliary Beat Frequency (CBF) of Nasal Epithelial Cell Cilia (ECC) in Chronic Obstructive Pulmonary Disease (COPD). American Journal of Respiratory and Critical Care Medicine. 2009
- Long Term Safety of Bronchial Thermoplasty (BT): 3 Year Data from Multiple Studies.. American Journal of Respiratory and Critical Care Medicine. 2009
- Validation of the Asthma Control Questionnaire in Children.. American Journal of Respiratory and Critical Care Medicine. 2009
- Who Gets Directly Observed Therapy? Use of a Risk Management Tool To Identify TB Patients at Greatest Need. American Journal of Respiratory and Critical Care Medicine. 2009
- AN AUDIT TO ASSESS THE ACCURACY OF POSITRON EMISSION TOMOGRAPHY SCANNING IN LUNG CANCER. Thorax. A69-A70. 2008
- Audit of lung cancer waiting times at a district general hospital. Thorax. A72-A72. 2007
- Intercostal drain insertion: A survey of general medical registrars in the mid trent region. Thorax. A101-A102. 2007
- Smoking cessation advice for hospital inpatients: Room for improvement. Thorax. A13-A14. 2007
- A microwell-based galactose oxidase-Schiff's assay for Thomsen-Friedenreich antigen in diagnosis of lung cancer. Clinical Chemistry. A166-A166. 2006
- Hypoxia inducible factor (HIF)-1 alpha in non-small cell lung cancer (NSCLC). British Journal of Cancer. S28-S28. 2002
- beta-catenin in non-small cell lung cancer (NSCLC). British Journal of Cancer. S59-S60. 2002
- Her2 gene amplification and protein expression in non-small cell lung cancer. Thorax. A85-A85. 2000
- Analysis of the MMP-9 and Epidermal Growth Factor signal pathway in non small cell lung cancer (NSCLC) - A potential target for therapeutic intervention. Journal of Pathology. 7A-7A. 2000
- Expression and prognostic influence of MMP-2, MMP-9 and TIMP-2 in non-small cell lung cancer. Thorax. A83-A83. 1999
- Increased Chalkley microvessel counts are related to platelet count and convey poor prognosis in malignant mesothelioma. Thorax. A81-A81. 1999
- Increased platelet and microvessel counts confer poor prognosis in operable non-small cell lung cancer. Thorax. A20-A20. 1999
- MMP-9 and the epidermal growth factor signal pathway in non-small cell lung cancer. Thorax. A82-A82. 1999
- Prognostic significance of platelet microvessel counts in non-small cell lung cancer. British Journal of Cancer. 89-89. 1999
- A comparison of nicotine replacement combined with a novel compound (ProBAN (TM)) and nicotine replacement alone for smoking cessation. American Journal of Respiratory and Critical Care Medicine. A735-A735. 1999
- Allergic airways responses are associated with enhanced parasympathetic tone.. American Journal of Respiratory and Critical Care Medicine. A535-A535. 1999
- Effect of high frequency chest wall oscilation on the central and peripheral distribution of aerosolized DTPA as compared to standard chest physiotherapy in cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. A686-A686. 1999
- Intense bcl-2 immunostaining confers a poor prognosis in non-small cell lung cancer. American Journal of Respiratory and Critical Care Medicine. A202-A202. 1999
- Neutrophil survival is stimulated by soluble factors released from platelets.. American Journal of Respiratory and Critical Care Medicine. A91-A91. 1999
- REGULATION OF NEUTROPHIL APOPTOSIS BY PROTEIN-KINASE-C AND TYROSINE KINASE PATHWAYS. American Review of Respiratory Disease. A300-A300. 1993
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journal articles
- The Clinical Frailty Scale for Risk Stratification in Patients With Fibrotic Interstitial Lung Disease. Chest. 166:517-527. 2024
- Characteristics and risk factors of interstitial pneumonia with autoimmune features. Respiratory Medicine. 221:107500-107500. 2024
- Integration and Application of Radiologic Patterns From Clinical Practice Guidelines on Idiopathic Pulmonary Fibrosis and Fibrotic Hypersensitivity Pneumonitis. Chest. 164:1466-1475. 2023
- Predicting New-onset Exertional and Resting Hypoxemia in Fibrotic Interstitial Lung Disease. Annals of the American Thoracic Society. 20:1726-1734. 2023
- Eosinophil-independent IL-5 levels are increased in critically ill COVID-19 patients who survive. Allergy, Asthma and Clinical Immunology. 19:58. 2023
- Eligibility criteria from pharmaceutical randomised controlled trials of idiopathic pulmonary fibrosis: a registry-based study. European Respiratory Journal. 61:2202163-2202163. 2023
- Patient Characteristics and Survival for Progressive Pulmonary Fibrosis Using Different Definitions. American Journal of Respiratory and Critical Care Medicine. 207:102-105. 2023
- Infliximab therapy in refractory sarcoidosis: a multicenter real-world analysis. Respiratory Research. 23:54. 2022
- Clinical relevance of rheumatoid factor and anti‐citrullinated peptides in fibrotic interstitial lung disease. Respirology. 27:854-862. 2022
- Prevalence and characteristics of progressive fibrosing interstitial lung disease in a prospective registry. European Respiratory Journal. 60:2102571-2102571. 2022
- Artichoke phytocomplex modulates serum microRNAs in patients exposed to asbestos: a first step of a phase II clinical trial. Journal of Experimental and Clinical Cancer Research. 41:255. 2022
- Prescribing Patterns and Tolerability of Mycophenolate and Azathioprine in Patients with Nonidiopathic Pulmonary Fibrosis Fibrotic Interstitial Lung Disease. Annals of the American Thoracic Society. 19:863-867. 2022
- Effect of continued antifibrotic therapy after forced vital capacity decline in patients with idiopathic pulmonary fibrosis; a real world multicenter cohort study. Respiratory Medicine. 191:106722-106722. 2022
- Travel Distance to Subspecialty Clinic and Outcomes in Patients with Fibrotic Interstitial Lung Disease. Annals of the American Thoracic Society. 19:20-27. 2022
- Validation and minimum important difference of the UCSD Shortness of Breath Questionnaire in fibrotic interstitial lung disease. Respiratory Research. 22:202. 2021
- Treatment Initiation in Patients with Interstitial Lung Disease in Canada. Annals of the American Thoracic Society. 18:1661-1668. 2021
- Comprehensive Care Management in Conjunction with Sputum Cytometry-Guided Pharmacotherapy in a Post-Discharge Clinic for Patients with COPD. COPD: Journal of Chronic Obstructive Pulmonary Disease. 18:411-416. 2021
- Bronchial thermoplasty guided by hyperpolarised gas magnetic resonance imaging in adults with severe asthma: a 1-year pilot randomised trial. ERJ Open Research. 7:00268-2021. 2021
- Prevalence and prognostic impact of physical frailty in interstitial lung disease: A prospective cohort study. Respirology. 26:683-689. 2021
- CanVasc Consensus Recommendations for the Management of Antineutrophil Cytoplasm Antibody-associated Vasculitis: 2020 Update. Journal of Rheumatology. 48:555-566. 2021
- Parkinson’s disease dystonia as a cause of respiratory distress and stridor. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 5:69-71. 2021
- Development and validation of an open-source, disposable, 3D-printed in vitro environmental exposure system for Transwell culture inserts. ERJ Open Research. 7:00705-2020. 2021
- Eosinophilia and Response to Bronchial Thermoplasty. American Journal of Respiratory and Critical Care Medicine. 203:148-148. 2021
- Minimum important difference of the EQ-5D-5L and EQ-VAS in fibrotic interstitial lung disease. Thorax. 76:37-43. 2021
- A cluster-based analysis evaluating the impact of comorbidities in fibrotic interstitial lung disease. Respiratory Research. 21:322. 2020
- Lessons of the month: A breathless severe asthmatic in the genomic era: Occam's razor or Hickam's dictum?. Clinical Medicine. 20:e264-e266. 2020
- Real-world patterns of pirfenidone use and safety in patients with idiopathic pulmonary fibrosis in Canada: Data from INSPIRATION PLUS. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 4:25-30. 2020
- ABCF1 Regulates dsDNA-induced Immune Responses in Human Airway Epithelial Cells. Frontiers in Cellular and Infection Microbiology. 10:487. 2020
- A cross-sectional evaluation of the idiopathic pulmonary fibrosis patient satisfaction and quality of life with a care coordinator. Journal of Thoracic Disease. 11:5547-5556. 2019
- Costs of Workplace Productivity Loss in Patients With Fibrotic Interstitial Lung Disease. Chest. 156:887-895. 2019
- Optimizing sputum cell counts prior to bronchial thermoplasty: A preliminary report. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 3:143-147. 2019
- A female patient with recurrent lung lesion and hilar lymphadenopathy. Journal of Thoracic Disease. 9:1858-1863. 2017
- Acute exacerbations of idiopathic pulmonary fibrosis: tough to define; tougher to manage. European Respiratory Journal. 49:1700811-1700811. 2017
- Preliminary Results of the Adoption and Application of the Integrated Comprehensive Care Bundle Care Program When Treating Patients with Chronic Obstructive Pulmonary Disease. Canadian Respiratory Journal. 2017:1-10. 2017
- Online and Social Media Suicide Prevention Interventions for Young People: A Focus on Implementation and Moderation.. Journal of the Canadian Academy of Child and Adolescent Psychiatry. 25:80-86. 2016
- Comment on: International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. European Respiratory Journal. 44:267-267. 2014
- Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. Journal of Allergy and Clinical Immunology. 132:1295-1302. 2013
- Ciliary beating is depressed in nasal cilia from chronic obstructive pulmonary disease subjects. Respiratory Medicine. 106:1139-1147. 2012
- Early Neoproterozoic Basin Formation in Yukon, Canada: Implications for the make-up and break-up of Rodinia. Geoscience Canada. 39:77-99. 2012
- Asthma Outcomes from Bronchial Thermoplasty in the AIR2 trial. American Journal of Respiratory and Critical Care Medicine. 184:743-744. 2011
- Bronchial thermoplasty for severe asthma. Current Opinion in Pulmonary Medicine. 17:34-38. 2011
- From the authors. American Journal of Respiratory and Critical Care Medicine. 183:132-133. 2011
- Outcome Reporting in Asthma Research. American Journal of Respiratory and Critical Care Medicine. 183:132-133. 2011
- Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma. American Journal of Respiratory and Critical Care Medicine. 182:1565-1567. 2010
- Bronchial Thermoplasty in Developing Countries: Is It Really Worth It?. American Journal of Respiratory and Critical Care Medicine. 182:719-719. 2010
- Bronchial Thermoplasty. Clinics in Chest Medicine. 31:135-140. 2010
- Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma. American Journal of Respiratory and Critical Care Medicine. 181:116-124. 2010
- Letter to the Editor. Canadian Respiratory Journal. 17:236-236. 2010
- Treating IPF—all or nothing? A PRO‐CON debate. Respirology. 14:1072-1081. 2009
- Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 179:588-594. 2009
- Approach to chronic obstructive pulmonary disease in primary care.. Canadian Family Physician. 54:706-711. 2008
- New interventions in asthma including bronchial thermoplasty. Current Opinion in Pulmonary Medicine. 14:77-81. 2008
- Safety and Efficacy of Bronchial Thermoplasty in Symptomatic, Severe Asthma. American Journal of Respiratory and Critical Care Medicine. 176:1185-1191. 2007
- Redarkening of Port-Wine Stains 10 Years after Laser Treatment. New England Journal of Medicine. 356:2745-2746. 2007
- Asthma Control during the Year after Bronchial Thermoplasty. New England Journal of Medicine. 356:1327-1337. 2007
- Global assessment after bronchial thermoplasty: The patient's perspective. Journal of Medical Economics. 10:37-46. 2006
- Cell-specific Gene Expression in Patients with Usual Interstitial Pneumonia. American Journal of Respiratory and Critical Care Medicine. 174:557-565. 2006
- Bronchial Thermoplasty for Asthma. American Journal of Respiratory and Critical Care Medicine. 173:965-969. 2006
- Respirology research in Canada: The future looks bright!. Canadian Respiratory Journal. 13:101. 2006
- Cyclooxygenase-2 protein levels are independent of epidermal growth factor receptor expression or activation in operable non-small cell lung cancer. Lung Cancer. 48:47-57. 2005
- Lung Volume Reduction Surgery vs Medical Treatment*. Chest. 127:1166-1166. 2005
- B cell non-Hodgkin's lymphoma of the trachea mimicking COPD. Thorax. 59:1100-1100. 2004
- Coexpression of epidermal growth factor receptor with related factors is associated with a poor prognosis in non-small-cell lung cancer. British Journal of Cancer. 91:1301-1307. 2004
- Hypoxia‐inducible factor‐1α in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways. International Journal of Cancer. 111:43-50. 2004
- Effect of freezing of sputum samples on flow cytometric analysis of lymphocyte subsets. European Respiratory Journal. 24:309-312. 2004
- Cigarette Smoke Decreases Pulmonary Dendritic Cells and Impacts Antiviral Immune Responsiveness. American Journal of Respiratory Cell and Molecular Biology. 30:202-211. 2004
- A method to preserve sputum for delayed examination. European Respiratory Journal. 22:996-1000. 2003
- Epidermal growth factor receptors and cyclooxygenase-2 in the pathogenesis of non-small cell lung cancer: potential targets for chemoprevention and systemic therapy. Lung Cancer. 39:1-13. 2003
- Cysteinyl Leukotrienes Promote Human Airway Smooth Muscle Migration. American Journal of Respiratory and Critical Care Medicine. 166:738-742. 2002
- Tumour necrosis is an independent prognostic marker in non-small cell lung cancer: correlation with biological variables. Lung Cancer. 37:235-240. 2002
- Bcl-2 is an independent prognostic factor and adds to a biological model for predicting outcome in operable non-small cell lung cancer. Lung Cancer. 34:417-426. 2001
- Towards a biological staging model for operable non-small cell lung cancer. Lung Cancer. 34:S83-S89. 2001
- Increased detection of interleukin-;5 in sputum by addition of protease inhibitors. European Respiratory Journal. 18:685-691. 2001
- A biological staging model for operable non-small cell lung cancer. Thorax. 56:561-566. 2001
- Herceptest: Her2 expression and gene amplification in non-small cell lung cancer. International Journal of Cancer. 92:480-483. 2001
- Coronary and laryngeal spasm provoked by methacholine inhalation. Journal of Allergy and Clinical Immunology. 107:392-393. 2001
- Nicotine Replacement Combined with a Novel Compound (ProBAN) for Smoking Cessation: A Pilot Study. Canadian Respiratory Journal. 8:21-26. 2001
- Gemcitabine and paclitaxel associated pneumonitis in non-small cell lung cancer. European Journal of Cancer. 36:2329-2334. 2000
- A randomized, controlled trial comparing thoracoscopy and limited thoracotomy for lung biopsy in interstitial lung disease. Annals of Thoracic Surgery. 70:1647-1650. 2000
- Amiodarone and the lung: wide variations in clinical practice. Respiratory Medicine. 94:1130-1131. 2000
- Prognostic significance of platelet and microvessel counts in operable non-small cell lung cancer. Lung Cancer. 29:169-177. 2000
- Does immunointensity account for the differences in prognostic significance of Bcl-2 expression in non-small cell lung cancer?. Pathology Oncology Research. 6:87-92. 2000
- Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer.. Clinical Cancer Research. 6:2349-2355. 2000
- Coexpression of MUC1 glycoprotein with multiple angiogenic factors in non-small cell lung cancer suggests coactivation of angiogenic and migration pathways.. Clinical Cancer Research. 6:1917-1921. 2000
- NO+but not NO radical relaxes airway smooth muscle via cGMP-independent release of internal Ca2+. American Journal of Physiology - Lung Cellular and Molecular Physiology. 278:L899-L905. 2000
- Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer. British Journal of Cancer. 82:1427-1432. 2000
- Angiogenesis and non-small cell lung cancer. Lung Cancer. 27:81-100. 2000
- The plasmin cascade and matrix metalloproteinases in non-small cell lung cancer. Thorax. 54:169-179. 1999
- Lung Volume Reduction for Emphysema and The Canadian Lung Volume Reduction (CLVR) Surgery Project. Canadian Respiratory Journal. 6:26-32. 1999
- Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: Inflammatory cells, lymphocyte subsets and soluble markers compared. Pneumologie. 52:401. 1998
- A Randomized Trial of Vascular Hemostasis Techniques to Reduce Femoral Vascular Complications After Coronary Intervention 11This study was designed, supported, and internally funded by the staff of Duke University Medical Center.. American Journal of Cardiology. 81:970-976. 1998
- Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: inflammatory cells, lymphocyte subsets and soluble markers compared. European Respiratory Journal. 11:828-834. 1998
- Regulation of Apoptosis by IL-10 in the Resolution of Inflammatory Responses to Infection. Sepsis. 2:73-78. 1998
- The role of neutrophils in inflammation.. Canadian Respiratory Journal. 5 Suppl A:37A-40A. 1998
- IL-10 enhances resolution of pulmonary inflammation in vivo by promoting apoptosis of neutrophils. American Journal of Physiology - Lung Cellular and Molecular Physiology. 271:L566-L571. 1996
- Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo.. American Journal of Respiratory Cell and Molecular Biology. 12:232-237. 1995
- Fourier transform spectroscopy of the Herzberg I bands of O2. Canadian Journal of Physics. 72:1101-1108. 1994
- Growth and Colony‐Stimulating Factors Mediate Eosinophil Fibroblast Interactions in Chronic Airway Inflammationa. Annals of the New York Academy of Sciences. 725:83-90. 1994
- Manganese superoxide dismutase and heat shock protein 70 are not necessary for suppression of apoptosis in human peripheral blood neutrophils.. American Journal of Respiratory Cell and Molecular Biology. 10:493-498. 1994
- CYTOKINES .4. CYTOKINES AND PULMONARY FIBROSIS. Thorax. 48:931-935. 1993
- Cytokines and pulmonary fibrosis.. Thorax. 48:931-935. 1993
- Bronchial Epithelial Cell-derived Cytokines (G-CSF and GM-CSF Promote the Survical of Peripheral Blood Neutrophils In Vitro. American Journal of Respiratory Cell and Molecular Biology. 7:507-514. 1992
- FIBROBLASTS AND OTHER STRUCTURAL CELLS IN AIRWAY INFLAMMATION. American Review of Respiratory Disease. 145:S14-S17. 1992
- Fibroblasts and Other Structural Cells in Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 145:S14-S17. 1992
- Promotion of Eosinophil Survival by Human Bronchial Epithelial Cells and its Modulation by Steroids. American Journal of Respiratory Cell and Molecular Biology. 4:525-531. 1991
- Monocyte-Macrophage Differentiation Induced by Human Upper Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology. 4:255-263. 1991
- Neutrophilic Differentiation Induced by Human Upper Airway Fibroblast-derived Granulocyte/Macrophage Colony-stimulating Factor (GM-CSF). American Journal of Respiratory Cell and Molecular Biology. 4:11-17. 1991
- Human Lung Fibroblast-derived Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Mediates Eosinophil Survival In Vitro. American Journal of Respiratory Cell and Molecular Biology. 1:289-295. 1989
- Adele Marie Barker. The Mother Syndrome in The Russian Folk Imagination. Columbus, Ohio: Slavica, 1986. 180 pp. $14.95. (paper).. Canadian-American Slavic Studies. 22:486-487. 1988