selected scholarly activity
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journal articles
- Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.. Nature Genetics. 57:1389-1401. 2025
- Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci. medRxiv. 2024.03.13.24304161. 2024
- Trans-diagnostic determinants of psychotherapeutic treatment response: The pressing need and new opportunities for a more systematic way of selecting psychotherapeutic treatment in the age of virtual service delivery. Frontiers in Public Health. 11:1102434. 2023
- The Translational Machine: A novel machine‐learning approach to illuminate complex genetic architectures. Genetic Epidemiology. 45:485-536. 2021
- Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder. Translational Psychiatry. 11:91. 2021
- Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea.. Cochrane Database of Systematic Reviews. 4:CD007736. 2020
- Sex differences in the genetic architecture of obsessive–compulsive disorder. American Journal of Medical Genetics, Part B, Neuropsychiatric Genetics. 180:351-364. 2019
- Revealing the complex genetic architecture of obsessive–compulsive disorder using meta-analysis. Molecular Psychiatry. 23:1181-1188. 2018
- Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD. European Neuropsychopharmacology. 27:657-666. 2017
- Genome Wide Association Study (GWAS) between Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD). Frontiers in Molecular Neuroscience. 10:83. 2017
- Whole-genome association analysis of treatment response in obsessive-compulsive disorder. Molecular Psychiatry. 21:270-276. 2016
- Prediction of remission in obsessive compulsive disorder using a novel machine learning strategy. International Journal of Methods in Psychiatric Research. 24:156-169. 2015
- Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS. Molecular Psychiatry. 20:337-344. 2015
- Editorial: “Ion channels and mental illness: exploring etiology and pathophysiology in major psychiatric disorders”. Frontiers in Genetics. 6:152. 2015
- Isoforms of the neuronal glutamate transporter gene, SLC1A1/EAAC1, negatively modulate glutamate uptake: relevance to obsessive-compulsive disorder.. Translational Psychiatry. 3:e259. 2013
- Gene ontology analysis of pairwise genetic associations in two genome-wide studies of sporadic ALS. BioData Mining. 5:9. 2012
- Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing.. Human Genetics. 131:373-391. 2012
- Comparative Linkage Meta-Analysis Reveals Regionally-Distinct, Disparate Genetic Architectures: Application to Bipolar Disorder and Schizophrenia. PLoS ONE. 6:e19073-e19073. 2011
- Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission.. Human Genetics. 125:63-79. 2009
- The evolution of deep brain stimulation for neuropsychiatric disorders. Frontiers in Bioscience - Landmark. Volume:4638-4638. 2008
- Determinants of prostate cancer stage in northern New England: USA Franco-American contextual effects. Social Science and Medicine. 65:2018-2030. 2007
- Cancer of the Colorectum in Maine, 1995‐1998: Determinants of Stage at Diagnosis in a Rural State. Journal of Rural Health. 23:25-32. 2007
- Toward a biaxial model of "bipolar" affective disorders: further exploration of genetic, molecular and cellular substrates.. Journal of Affective Disorders. 94:35-66. 2006
- Toward a biaxial model of "bipolar" affective disorders: spectrum phenotypes as the products of neuroelectrical and neurochemical alterations.. Journal of Affective Disorders. 94:15-33. 2006
- Antidepressants for Bipolar Depression. American Journal of Psychiatry. 162:1545-1546. 2005
- Antidepressants for Bipolar Depression. American Journal of Psychiatry. 162:1546-1546. 2005
- Practice guideline for the treatment of patients with acute stress disorder and posttraumatic stress disorder. American Journal of Psychiatry. 161. 2004
- Practice guideline for the treatment of patients with schizophrenia, second edition. American Journal of Psychiatry. 161:1-56. 2004
- Practice guideline for the treatment of patients with schizophrenia, second edition.. American Journal of Psychiatry. 161:1-56. 2004
- A Public Health Response to a Cluster of Suicidal Behaviors: Clinical Psychiatry, Prevention, and Community Health. Journal of Psychiatric Practice. 9:219-227. 2003
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preprints