selected scholarly activity
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conferences
- Probiotics in Critical Illness: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Critical Care Medicine. 1175-1186. 2022
- Diarrhea and Clostridum Difficile Infection in the ICU: a Multicenter Study. Gastroenterology. S942-S942. 2017
- Cycle Pilot Rct: A Multicenter Feasibility Study Of Early In-Bed Cycling Versus Routine Physiotherapy In Medical- Surgical Ventilated Patients. American Journal of Respiratory and Critical Care Medicine. 2017
- LONG-TERM IMPACT OF MODE OF DELIVERY ON STRESS URINARY INCONTINENCE AND URGENCY URINARY INCONTINENCE: A SYSTEMATIC REVIEW AND META-ANALYSIS.. Journal of Urology. E587-E587. 2016
- DIARRHEA DURING CRITICAL ILLNESS. Critical Care Medicine. 2015
- SCREENING WEEKS: A PILOT TRIAL MANAGEMENT METRIC. Critical Care Medicine. 2015
- LONG-TERM IMPACT OF MODE OF DELIVERY ON STRESS AND URGENCY URINARY INCONTINENCE: A SYSTEMATIC REVIEW AND META-ANALYSIS. Neurourology and Urodynamics. S174-S175. 2015
- Perioperative Mortality and Myocardial Injury Among Patients With Prior High-Risk Cardiac Events Undergoing Non-Cardiac Surgery: A VISON Substudy. Circulation. 2014
- Nonleg Venous Thrombosis in Critically Ill Adults. JAMA Internal Medicine. 689-689. 2014
- Risk Of Thromboses From Peripherally Inserted Central Catheters (piccs) In The Icu. American Journal of Respiratory and Critical Care Medicine. 2014
- The Neurovision Pilot Study: Noncardiac Surgery Carries A Significant Risk Of Acute Covert Stroke. Stroke. 2013
- MAJOR BLEEDING IN MEDICAL-SURGICAL CRITICALLY ILL PATIENTS IS ASSOCIATED WITH INCREASED USE OF BLOOD PRODUCTS, LONGER HOSPITAL STAY AND HIGHER MORTALITY. Critical Care Medicine. U39-U40. 2012
- NON-LEG VENOUS THROMBI DURING CRITICAL ILLNESS: A NESTED PROSPECT WE COHORT STUDY. Critical Care Medicine. U208-U209. 2012
- THROMBOCYTOPENIA IN THE CRITICALLY ILL: INCIDENCE, RISK FACTORS AND IMPACT ON TRANSFUSIONS, BLEEDING, MORTALITY. Critical Care Medicine. U97-U97. 2012
- Can Low-Molecular-Weight Heparin Be Safely Used as Prophylaxis Against Venous Thromboembolism in Critically Ill Patients with End-Stage Renal Disease? A Subgroup Analysis of the Protect Trial. American Journal of Hematology. S199-S200. 2012
- Laboratory HIT Testing in Critically III Patients. Blood. 93-93. 2011
- A clinically sensitive cardiac troponin I assay (AccuTnI) versus the high sensitive cardiac troponin T assay to predict early serious cardiac outcomes in patients with potential acute coronary syndrome. Clinical Biochemistry. 1174-1174. 2011
- Methods Center Adjudication Costs For 5 Morbidity Outcomes In A Thromboprophylaxis Trial. American Journal of Respiratory and Critical Care Medicine. 2011
- Central Statistical Monitoring Of An International Thromboprophylaxis Trial. American Journal of Respiratory and Critical Care Medicine. 2010
- Adjudicating Bleeding Outcomes in a Large Thromboprophylaxis Trial in Critical Illness. Blood. 974-974. 2009
- Inter-Rater Reliability of the 4Ts Scoring System for Diagnosing Heparin-Induced Thrombocytopenia in Critically III Patients. Blood. 1535-1535. 2009
- Adjudication Calibration for Pulmonary Embolism in a Thromboprophylaxis Trial. American Journal of Respiratory and Critical Care Medicine. 2009
- Dalteparin Thromboprophylaxis in Critically Ill Patients with Severe Renal Insufficiency: The Direct Study.. Blood. 304-304. 2007
- A RANDOMIZED TRIAL OF STRATEGIES FOR ASSESSING ELIGIBILITY FOR LONG-TERM DOMICILIARY OXYGEN THERAPY. Chest. 254S-254S. 2005
- PGI9 RESPONSIVENESS TO CHANGE AND ENGLISH LANGUAGE VALIDATION OF THE WPAI-GERD QUESTIONNAIRE-RESULTS FROM A CANADIAN STUDY. Value in Health. 349-349. 2004
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journal articles
- The relative merits of using a high-sensitivity cardiac Troponin T assay compared to a nonhigh-sensitivity troponin T assay after noncardiac surgery. American Heart Journal. 275:45-52. 2024
- Osteochondroplasty with or without labral repair is more cost-effective than arthroscopic lavage with or without labral repair for treatment of young adults with femoroacetabular impingement: A cost-utility analysis based on data from a randomized controlled trial.. Journal of ISAKOS. 9:100307. 2024
- Proton pump inhibitors for gastrointestinal bleeding prophylaxis in critically ill patients: A systematic review protocol. Acta Anaesthesiologica Scandinavica. 68:983-988. 2024
- Time from injury to hip-fracture surgery in low-income and middle-income regions: a secondary analysis of data from the International Orthopaedic Multicentre Study in Fracture Care (INORMUS). The Lancet Healthy Longevity. 5:e552-e562. 2024
- Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation. New England Journal of Medicine. 391:9-20. 2024
- Adjudication of a primary trial outcome: Results of a calibration exercise and protocol for a large international trial. Contemporary Clinical Trials Communications. 39:101284-101284. 2024
- Protocol implementation during the COVID-19 pandemic: experiences from a randomized trial of stress ulcer prophylaxis. BMC Medical Research Methodology. 24:109. 2024
- Narrative medicine and death in the ICU: word clouds as a visual legacy. BMJ Supportive and Palliative Care. 14:e634-e641. 2024
- Follicle-Stimulating Hormone Exacerbates Cardiovascular Disease in the Presence of Low or Castrate Testosterone Levels. JACC: Basic to Translational Science. 9:364-379. 2024
- Skin Antisepsis before Surgical Fixation of Extremity Fractures. New England Journal of Medicine. 390:409-420. 2024
- One-year Outcomes after Discharge from Noncardiac Surgery and Association between Predischarge Complications and Death after Discharge: Analysis of the VISION Prospective Cohort Study. Anesthesiology. 140:8-24. 2024
- REVISE: re-evaluating the inhibition of stress erosions in the ICU—statistical analysis plan for a randomized trial. Trials. 24:796. 2023
- Myocardial Injury After Noncardiac Surgery in Major General Surgical Patients A Prospective Observational Cohort Study. Annals of Surgery. 278:e1192-e1197. 2023
- REVISE:Re-Evaluating theInhibition ofStressErosions in the ICU: a randomised trial protocol. BMJ Open. 13:e075588-e075588. 2023
- Proton pump inhibitors in critically ill mechanically ventilated patients with COVID-19: protocol for a substudy of the Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial. Trials. 24:561. 2023
- Reamed compared with unreamed nailing of tibial shaft fractures: Does the initial method of nail insertion influence outcome in patients requiring reoperations?. Canadian Journal of Surgery. 66:E384-E389. 2023
- Critical Care Cycling to ImproveLowerExtremity Strength (CYCLE): protocol for an international, multicentre randomised clinical trial of early in-bed cycling for mechanically ventilated patients. BMJ Open. 13:e075685-e075685. 2023
- Clostridioides difficile infection in mechanically ventilated critically ill patients: A nested cohort study. Journal of Critical Care. 75:154254-154254. 2023
- Definitions, rates and associated mortality of ICU-acquired pneumonia: A multicenter cohort study. Journal of Critical Care. 75:154284-154284. 2023
- Sex differences in thromboprophylaxis of the critically ill: a secondary analysis of a randomized trial. Canadian Journal of Anaesthesia. 70:1008-1018. 2023
- The impact of heterotopic ossification prophylaxis after surgical fixation of acetabular fractures: national treatment patterns and related outcomes. Injury. 54:1693-1701. 2023
- Association of Preoperative Growth Differentiation Factor-15 Concentrations and Postoperative Cardiovascular Events after Major Noncardiac Surgery. Anesthesiology. 138:508-522. 2023
- High-sensitivity Troponin I Predicts Major Cardiovascular Events after Non-Cardiac Surgery: A Vascular Events in Non-Cardiac Surgery Patients Cohort Evaluation (VISION) Substudy. Clinical Chemistry. 69:492-499. 2023
- Change in Gustilo-Anderson classification at time of surgery does not increase risk for surgical site infection in patients with open fractures: A secondary analysis of a multicenter, prospective randomized controlled trial. OTA Int. 6:e231-e231. 2023
- High-Sensitivity Cardiac Troponin I Thresholds to Identify Myocardial Injury After Noncardiac Surgery: A Cohort Study. Canadian Journal of Cardiology. 39:311-318. 2023
- Correction: Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): protocol for a randomized controlled trial. Trials. 24:142. 2023
- Enhancing end of life care on general internal medical wards: the 3 Wishes Project. BMC Palliative Care. 22:11. 2023
- Health economic evaluation alongside the Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (E-PROSPECT): a cost-effectiveness analysis. Canadian Journal of Anaesthesia. 69:1515-1526. 2022
- Patients With Femoral Neck Fractures Are at Risk for Conversion to Arthroplasty After Internal Fixation: A Machine‐learning Algorithm. Clinical Orthopaedics and Related Research. 480:2350-2360. 2022
- Academic and Community ICUs Participating in a Critical Care Randomized Trial: A Comparison of Patient Characteristics and Trial Metrics. Critical Care Explorations. 4:e0794-e0794. 2022
- Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): protocol for a randomized controlled trial. Trials. 23:894. 2022
- Predictors of Functional Recovery among Musculoskeletal Oncology Patients Undergoing Lower Extremity Endoprosthetic Reconstruction. Current Oncology. 29:7598-7606. 2022
- Determinants of tobacco smoking abstinence one year after major noncardiac surgery: a secondary analysis of the VISION study. British Journal of Anaesthesia. 129:497-505. 2022
- Monitoring and auditing protocol adherence, data integrity and ethical conduct of a randomized clinical trial: A case study. Journal of Critical Care. 71:154094-154094. 2022
- A pragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solutions in open fractures (Aqueous-PREP): statistical analysis plan. Trials. 23:772. 2022
- Prospective evaluation of sport activity and the development of femoroacetabular impingement in the adolescent hip (PREVIEW): results of the pilot study. Pilot and Feasibility Studies. 8:201. 2022
- Who, if anyone, may benefit from a total hip arthroplasty after a displaced femoral neck fracture?. Bone and Joint Open. 3:611-617. 2022
- Predictors of 1-year mortality after adult lung transplantation: Systematic review and meta-analyses. The Journal of Heart and Lung Transplantation. 41:937-951. 2022
- Effect of Osteochondroplasty on Time to Reoperation After Arthroscopic Management of Femoroacetabular Impingement: Analysis of a Randomized Controlled Trial. Orthopaedic Journal of Sports Medicine. 10:23259671211041400. 2022
- Comparison of Prophylactic Intravenous Antibiotic Regimens After Endoprosthetic Reconstruction for Lower Extremity Bone Tumors. JAMA Oncology. 8:345-345. 2022
- Osteochondroplasty Benefits the Pragmatic Patient With Femoroacetabular Impingement: Analysis From the Embedded Prospective Cohort of the Femoroacetabular Impingement RandomiSed Controlled Trial (FIRST). Arthroscopy: The Journal of Arthroscopy And Related. 38:818-830.e1. 2022
- Effect of Lactobacillus rhamnosus GG on Incident Pneumonia in Critically Ill Patients—Reply. Journal of the American Medical Association (JAMA). 327:182-182. 2022
- Pragmatic randomized trial evaluating pre-operative aqueous antiseptic skin solution in open fractures (Aqueous-PREP): the feasibility of a cluster randomized crossover study. Pilot and Feasibility Studies. 7:61. 2021
- Prophylactic Antibiotic Regimens In Tumor Surgery (PARITY): a multi-center randomized controlled study comparing alternative antibiotic regimens in patients undergoing tumor resections with endoprosthetic replacements—a statistical analysis plan. Trials. 22:223. 2021
- Scale-up and sustainability of a personalized end-of-life care intervention: a longitudinal mixed-methods study. BMC Health Services Research. 21:218. 2021
- Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): The Exploratory Health-Related Quality of Life and Patient-Reported Functional Outcomes of a Multi-Centre 2 × 2 Factorial Randomized Controlled Pilot Trial in Young Femoral Neck Fracture Patients. Injury. 52:3051-3059. 2021
- Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients. Journal of the American Medical Association (JAMA). 326:1024-1024. 2021
- Heterotopic Ossification Following Arthroplasty for Femoral Neck Fracture. Journal of Bone and Joint Surgery. American volume. 103:1328-1334. 2021
- Community implementation of the 3 Wishes Project: an observational study of a compassionate end-of-life care initiative for critically ill patients. CMAJ open. 9:E757-E764. 2021
- Impact of centre volume, surgeon volume, surgeon experience and geographic location on reoperation after intramedullary nailing of tibial shaft fractures. Canadian Journal of Surgery. 64:E371-E376. 2021
- Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials. Contemporary Clinical Trials Communications. 22:100787-100787. 2021
- The effect of time to irrigation and debridement on the rate of reoperation in open fractures. The Bone & Joint Journal. 103-B:1055-1062. 2021
- Femoroacetabular impingement surgery leads to early pain relief but minimal functional gains past 6 months: experience from the FIRST trial. Knee Surgery, Sports Traumatology, Arthroscopy. 29:1362-1369. 2021
- Lower body mass index and age are predictive of improved pain and health utility scores following arthroscopic management of femoroacetabular impingement. Knee Surgery, Sports Traumatology, Arthroscopy. 29:1461-1473. 2021
- Clinician Perspectives on Caring for Dying Patients During the Pandemic. ACP journal club. 174:493-500. 2021
- Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial. Contemporary Clinical Trials Communications. 21:100730-100730. 2021
- Osteochondroplasty and Labral Repair for the Treatment of Young Adults With Femoroacetabular Impingement: A Randomized Controlled Trial. American Journal of Sports Medicine. 49:25-34. 2021
- Prognostic factors for predicting health-related quality of life after intramedullary nailing of tibial fractures: a randomized controlled trial. Bone and Joint Open. 2:22-32. 2021
- The Association between Frailty and Short-Term Outcomes in an Intensive Care Unit Rehabilitation Trial: An Exploratory Analysis. Journal of Frailty and Aging. 10:1-7. 2021
- Risk Factors Associated With Infection in Open Fractures of the Upper and Lower Extremities. Journal of the American Academy of Orthopaedic Surgeons Global Research and Reviews. 4:e20.00188-e20.00188. 2020
- Preoperative levels of natriuretic peptides and the incidence of postoperative atrial fibrillation after noncardiac surgery: a prospective cohort study. CANADIAN MEDICAL ASSOCIATION JOURNAL. 192:E1715-E1722. 2020
- Correction to: Cluster identification, selection, and description in Cluster randomized crossover trials: the PREP-IT trials. Trials. 21:821. 2020
- Protocol for a multicenter prospective cohort study evaluating sport activity and development of femoroacetabular impingement in the adolescent hip. BMC Musculoskeletal Disorders. 21:221. 2020
- Arthroplasty Versus Internal Fixation for the Treatment of Undisplaced Femoral Neck Fractures: A Retrospective Cohort Study. Journal of Orthopaedic Trauma. 34:S9-S14. 2020
- Factors Associated With Mortality After Surgical Management of Femoral Neck Fractures. Journal of Orthopaedic Trauma. 34:S15-S21. 2020
- Is Total Hip Arthroplasty a Cost-Effective Option for Management of Displaced Femoral Neck Fractures? A Trial-Based Analysis of the HEALTH Study. Journal of Orthopaedic Trauma. 34:S37-S41. 2020
- Predictors of Long-Term Pain After Hip Arthroplasty in Patients With Femoral Neck Fractures: A Cohort Study. Journal of Orthopaedic Trauma. 34:S55-S63. 2020
- Predictors of Medical Serious Adverse Events in Hip Fracture Patients Treated With Arthroplasty. Journal of Orthopaedic Trauma. 34:S42-S48. 2020
- What Factors Increase Revision Surgery Risk When Treating Displaced Femoral Neck Fractures With Arthroplasty: A Secondary Analysis of the HEALTH Trial. Journal of Orthopaedic Trauma. 34:S49-S54. 2020
- What Predicts Health-Related Quality of Life for Patients With Displaced Femoral Neck Fractures Managed With Arthroplasty? A Secondary Analysis of the HEALTH Trial. Journal of Orthopaedic Trauma. 34:S29-S36. 2020
- Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): The Clinical Outcomes of a Multicenter 2 × 2 Factorial Randomized Controlled Pilot Trial in Young Femoral Neck Fracture Patients. Journal of Orthopaedic Trauma. 34:524-532. 2020
- Re: The Impact of Nocturia on Mortality: A Systematic Review and Meta-Analysis. Investigative Urology. 204:589-590. 2020
- Drug treatments for covid-19: living systematic review and network meta-analysis. The BMJ. 370:m2980-m2980. 2020
- Preoperative N-Terminal Pro–B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery. ACP journal club. 172:843-843. 2020
- Early Radiographic Union Score for Hip Is Predictive of Femoral Neck Fracture Complications Within 2 Years. Journal of Orthopaedic Trauma. 34:e195-e202. 2020
- Economic evaluation alongside the Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (E-PROSPECT): study protocol. BMJ Open. 10:e036047-e036047. 2020
- Fixation Using Alternative Implants for the Treatment of Hip Fractures. OTA Int. 3:e66-e66. 2020
- Association of Disability Benefits and/or Litigation With Time to Return to Work After Tibia Shaft Fracture Fixation. Journal of Occupational and Environmental Medicine. 62:370-374. 2020
- Delays in hospital admissions in patients with fractures across 18 low-income and middle-income countries (INORMUS): a prospective observational study. The Lancet Global Health. 8:e711-e720. 2020
- Effectiveness of Iodophor vs Chlorhexidine Solutions for Surgical Site Infections and Unplanned Reoperations for Patients Who Underwent Fracture Repair. JAMA network open. 3:e202215-e202215. 2020
- The Impact of Nocturia on Falls and Fractures: A Systematic Review and Meta-Analysis. Investigative Urology. 203:674-683. 2020
- The Impact of Nocturia on Mortality: A Systematic Review and Meta-Analysis. Investigative Urology. 203:486-495. 2020
- Preoperative N-Terminal Pro–B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery. ACP journal club. 172:96-96. 2020
- Compassionate End-of-Life Care: Mixed-Methods Multisite Evaluation of the 3 Wishes Project. ACP journal club. 172:1-1. 2020
- Motivators and Stressors for Canadian Research Coordinators in Critical Care: The MOTIVATE Survey. American Journal of Critical Care. 29:41-48. 2020
- Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture. New England Journal of Medicine. 381:2199-2208. 2019
- Fixation using alternative implants for the treatment of hip fractures (FAITH-2): design and rationale for a pilot multi-centre 2 × 2 factorial randomized controlled trial in young femoral neck fracture patients. Pilot and Feasibility Studies. 5:70. 2019
- Study protocol: design and rationale for an exploratory phase II randomized controlled trial to determine optimal vitamin D3 supplementation strategies for acute fracture healing. Pilot and Feasibility Studies. 5:135. 2019
- Association between complications and death within 30 days after noncardiac surgery. CANADIAN MEDICAL ASSOCIATION JOURNAL. 191:E830-E837. 2019
- Evaluating probiotics for the prevention of ventilator-associated pneumonia: a randomised placebo-controlled multicentre trial protocol and statistical analysis plan for PROSPECT. BMJ Open. 9:e025228-e025228. 2019
- Loss of Independence After Operative Management of Femoral Neck Fractures. Journal of Orthopaedic Trauma. 33:292-300. 2019
- Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients. BMJ Open Respiratory Research. 6:e000383-e000383. 2019
- Patient coping and expectations predict recovery after major orthopaedic trauma. British Journal of Anaesthesia. 122:51-59. 2019
- Are large clinical trials in orthopaedic trauma justified?. BMC Musculoskeletal Disorders. 19:124. 2018
- Femoroacetabular Impingement Randomised controlled Trial (FIRST) - a multi-centre randomized controlled trial comparing arthroscopic lavage and arthroscopic osteochondroplasty on patient important outcomes and quality of life in the treatment of young adult (18–50 years) femoroacetabular impingement: a statistical analysis plan. Trials. 19:588. 2018
- Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study. Respiratory Research. 19:245. 2018
- Prospective evaluation of intimate partner violence in fracture clinics (PRAISE-2): protocol for a multicentre pilot prospective cohort study. Pilot and Feasibility Studies. 4:115. 2018
- Myocardial Injury After Noncardiac Surgery (MINS) in Vascular Surgical Patients. Annals of Surgery. 268:357-363. 2018
- Wound Surface Area as a Risk Factor for Flap Complications among Patients with Open Fractures. Plastic and Reconstructive Surgery. 142:228-236. 2018
- Factors Associated With Revision Surgery After Internal Fixation of Hip Fractures. Journal of Orthopaedic Trauma. 32:223-230. 2018
- Factors associated with health-related quality of life, hip function, and health utility after operative management of femoral neck fractures. The Bone & Joint Journal. 100-B:361-369. 2018
- Correction to: Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials. Intensive Care Medicine. 44:277-278. 2018
- Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials. Intensive Care Medicine. 44:1-11. 2018
- Factors Associated With Health-Related Quality of Life in Patients With Open Fractures. Journal of Orthopaedic Trauma. 32:e5-e11. 2018
- Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial. PLoS ONE. 13:e0198285-e0198285. 2018
- Wound irrigation does not affect health-related quality of life after open fractures: results of a randomized controlled trial. The Bone & Joint Journal. 100-B:88-94. 2018
- Vitamin D Use and Health Outcomes After Surgery for Hip Fracture. Orthopedics. 40:e868-e875. 2017
- The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia. Research and Practice in Thrombosis and Haemostasis. 1:103-111. 2017
- Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery. Journal of the American Medical Association (JAMA). 317:1642-1642. 2017
- Fracture fixation in the operative management of hip fractures (FAITH): an international, multicentre, randomised controlled trial. The Lancet. 389:1519-1527. 2017
- Low intensity pulsed ultrasound for bone healing: systematic review of randomized controlled trials. The BMJ. 356:j656-j656. 2017
- Factors associated with the duration of disability benefits claims among Canadian workers: a retrospective cohort study. CMAJ open. 5:E109-E115. 2017
- Electronic nicotine delivery systems and/or electronic non-nicotine delivery systems for tobacco smoking cessation or reduction: a systematic review and meta-analysis. BMJ Open. 7:e012680-e012680. 2017
- GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence. Journal of Clinical Epidemiology. 87:14-22. 2017
- Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial—PROSPECT: a pilot trial. Trials. 17:377. 2016
- Risk factors for and prediction of mortality in critically ill medical–surgical patients receiving heparin thromboprophylaxis. Annals of Intensive Care. 6:18. 2016
- Hemicraniectomy versus medical treatment with large MCA infarct: a review and meta-analysis. BMJ Open. 6:e014390-e014390. 2016
- Re-evaluation of low intensity pulsed ultrasound in treatment of tibial fractures (TRUST): randomized clinical trial. The BMJ. 355:i5351-i5351. 2016
- Covert stroke after non-cardiac surgery: a prospective cohort study. British Journal of Anaesthesia. 117:191-197. 2016
- Incidence and Remission of Nocturia: A Systematic Review and Meta-analysis. European Urology. 70:372-381. 2016
- Long-term Impact of Mode of Delivery on Stress Urinary Incontinence and Urgency Urinary Incontinence: A Systematic Review and Meta-analysis. European Urology. 70:148-158. 2016
- Wound Irrigation Pressure Did Not Affect Reoperation Rate After Open Fracture Repair, but Normal Saline Solution Was Better Than Castile Soap. Journal of Bone and Joint Surgery. American volume. 98:871-871. 2016
- Character, Incidence, and Predictors of Knee Pain and Activity After Infrapatellar Intramedullary Nailing of an Isolated Tibia Fracture. Journal of Orthopaedic Trauma. 30:135-141. 2016
- Does Participation in a Randomized Clinical Trial Change Outcomes? An Evaluation of Patients Not Enrolled in the SPRINT Trial. Journal of Orthopaedic Trauma. 30:156-161. 2016
- Resident reflections on end-of-life education: a mixed-methods study of the 3 Wishes Project. BMJ Open. 6:e010626-e010626. 2016
- Meta-analysis of antibiotics versus appendicectomy for non-perforated acute appendicitis. British Journal of Surgery. 103:656-667. 2016
- A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds. New England Journal of Medicine. 373:2629-2641. 2015
- Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial—PROSPECT: protocol for a feasibility randomized pilot trial. Pilot and Feasibility Studies. 1:19. 2015
- INternational ORthopaedic MUlticentre Study (INORMUS) in Fracture Care. Journal of Orthopaedic Trauma. 29:S2-S6. 2015
- Competing Risk Analysis for Evaluation of Dalteparin Versus Unfractionated Heparin for Venous Thromboembolism in Medical-Surgical Critically Ill Patients. Medicine (United States). 94:e1479-e1479. 2015
- Fluid type and the use of renal replacement therapy in sepsis: a systematic review and network meta-analysis. Intensive Care Medicine. 41:1561-1571. 2015
- Prophylactic antibiotic regimens in tumour surgery (PARITY). Bone and Joint Research. 4:154-162. 2015
- Personalizing Death in the Intensive Care Unit: The 3 Wishes Project. ACP journal club. 163:271-279. 2015
- Association of worker characteristics and early reimbursement for physical therapy, chiropractic and opioid prescriptions with workers’ compensation claim duration, for cases of acute low back pain: an observational cohort study. BMJ Open. 5:e007836-e007836. 2015
- Which Surgical Treatment for Open Tibial Shaft Fractures Results in the Fewest Reoperations? A Network Meta-analysis. Clinical Orthopaedics and Related Research. 473:2179-2192. 2015
- Prognostic capabilities of coronary computed tomographic angiography before non-cardiac surgery: prospective cohort study. The BMJ. 350:h1907-h1907. 2015
- Failure of Anticoagulant Thromboprophylaxis. Critical Care Medicine. 43:401-410. 2015
- Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): study protocol for a randomized controlled trial. Trials. 15:502. 2014
- Fixation using alternative implants for the treatment of hip fractures (FAITH): design and rationale for a multi-centre randomized trial comparing sliding hip screws and cancellous screws on revision surgery rates and quality of life in the treatment of femoral neck fractures. BMC Musculoskeletal Disorders. 15:219. 2014
- Cost-effectiveness of Dalteparin vs Unfractionated Heparin for the Prevention of Venous Thromboembolism in Critically Ill Patients. Journal of the American Medical Association (JAMA). 312:2135-2135. 2014
- Critical-Sized Defect in the Tibia. Journal of Orthopaedic Trauma. 28:632-635. 2014
- Fluid Resuscitation in Sepsis. ACP journal club. 161:347-347. 2014
- Perceptions of authors' contributions are influenced by both byline order and designation of corresponding author. Journal of Clinical Epidemiology. 67:1049-1054. 2014
- Heparin-induced thrombocytopenia in the critically ill: Interpreting the 4Ts test in a randomized trial. Journal of Critical Care. 29:470.e7-470.e15. 2014
- Myocardial Injury after Noncardiac Surgery. Anesthesiology. 120:564-578. 2014
- Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers. Journal of Clinical Epidemiology. 67:560-570. 2014
- Correction: Association of Psychotherapy with Disability Benefit Claim Closure among Patients Disabled Due to Depression. PLoS ONE. 9:10.1371/annotation/fd8ade2b-e9ed-4f75-8e32-5b327535306c. 2014
- Prediction Scores Do Not Correlate with Clinically Adjudicated Categories of Pulmonary Embolism in Critically Ill Patients. Canadian Respiratory Journal. 21:36-42. 2014
- Thromboprophylaxis patterns and determinants in critically ill patients: a multicenter audit. Critical Care. 18:R82-R82. 2014
- Airways Disease Presenting as Restrictive Impairment: Response. Chest. 144:1979-1980. 2013
- Physicians declining patient enrollment in a critical care trial: a case study in thromboprophylaxis. Intensive Care Medicine. 39:2115-2125. 2013
- Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis. Intensive Care Medicine. 39:2135-2143. 2013
- Fluid resuscitation in severe sepsis and septic shock: systematic description of fluids used in randomized trials. Polskie Archiwum Medycyny Wewnetrznej. 123:603-608. 2013
- Thrombocytopenia in Critically Ill Patients Receiving Thromboprophylaxis. Chest. 144:1207-1215. 2013
- Heparin-Induced Thrombocytopenia in Medical Surgical Critical Illness. Chest. 144:848-858. 2013
- (Sample) Size Matters! An Examination of Sample Size From the SPRINT Trial Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients With Tibial Fractures. Journal of Orthopaedic Trauma. 27:183-188. 2013
- Adjudication of bleeding outcomes in an international thromboprophylaxis trial in critical illness. Thrombosis Research. 131:204-209. 2013
- Rates and determinants of informed consent: A case study of an international thromboprophylaxis trial. Journal of Critical Care. 28:28-39. 2013
- Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers. Journal of Clinical Epidemiology. 66:1014-1021. 2013
- Association of Psychotherapy with Disability Benefit Claim Closure among Patients Disabled Due to Depression. PLoS ONE. 8:e67162-e67162. 2013
- Co-enrollment of critically ill patients into multiple studies: patterns, predictors and consequences. Critical Care. 17:R1-R1. 2013
- Correction: Effectiveness of Cognitive Behavioral Therapy for Depression in Patients Receiving Disability Benefits: A Systematic Review and Individual Patient Data Meta-Analysis. PLoS ONE. 8:10.1371/annotation/d2692d0c-26c3-4a7d-b4f5-1139e051e59a. 2013
- Treatment effects on patient-important outcomes can be small, even with large effects on surrogate markers. Journal of Clinical Epidemiology. 65:940-945. 2012
- Error in Viewpoint in: Statin Therapy for Healthy Men Identified as ‘Increased Risk,’. Journal of the American Medical Association (JAMA). 307:2590-2590. 2012
- Association Between Postoperative Troponin Levels and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery. Journal of the American Medical Association (JAMA). 307:2295-2295. 2012
- Development and Validation of an Instrument to Predict Functional Recovery in Tibial Fracture Patients. Journal of Orthopaedic Trauma. 26:370-378. 2012
- Research ethics board approval for an international thromboprophylaxis trial. Journal of Critical Care. 27:225-231. 2012
- Credibility of claims of subgroup effects in randomised controlled trials: systematic review. The BMJ. 344:e1553-e1553. 2012
- Effectiveness of Cognitive Behavioral Therapy for Depression in Patients Receiving Disability Benefits: A Systematic Review and Individual Patient Data Meta-Analysis. PLoS ONE. 7:e50202-e50202. 2012
- Effects of higher-versus lower-protein diets on health outcomes: a systematic review and meta-analysis. European Journal of Clinical Nutrition. 66:780-780. 2012
- Reply to higher-versus lower-protein diets. European Journal of Clinical Nutrition. 66:1375-1375. 2012
- Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid. Journal of Clinical Epidemiology. 65:262-267. 2012
- Fluid Lavage of Open Wounds (FLOW): A Multicenter, Blinded, Factorial Pilot Trial Comparing Alternative Irrigating Solutions and Pressures in Patients With Open Fractures. Journal of Trauma and Acute Care Surgery. 71:596-606. 2011
- Economic Evaluation of Reamed versus Unreamed Intramedullary Nailing in Patients with Closed and Open Tibial Fractures: Results from the Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures (SPRINT). Value in Health. 14:450-457. 2011
- Dalteparin versus Unfractionated Heparin in Critically Ill Patients. New England Journal of Medicine. 364:1305-1314. 2011
- PROphylaxis for ThromboEmbolism in Critical Care Trial protocol and analysis plan. Journal of Critical Care. 26:223.e1-223.e9. 2011
- Prognostic Value of Troponin and Creatine Kinase Muscle and Brain Isoenzyme Measurement after Noncardiac Surgery. Anesthesiology. 114:796-806. 2011
- Is a Subgroup Claim Believable?. Journal of Bone and Joint Surgery. American volume. 93:e8-e8. 2011
- Identifying adults at risk of COPD who need confirmatory spirometry in primary care: Do symptom-based questions help?. Canadian Family Physician. 57:e51-e57. 2011
- An international prospective cohort study evaluating major vascular complications among patients undergoing noncardiac surgery: the VISION Pilot Study.. Open Medicine. 5:e193-e200. 2011
- The influence of study characteristics on reporting of subgroup analyses in randomised controlled trials: systematic review. The BMJ. 342:d1569-d1569. 2011
- Disease-specific education in the primary care setting increases the knowledge of people with chronic obstructive pulmonary disease: A randomized controlled trial. Patient Education and Counseling. 81:14-18. 2010
- Disease-specific education in the primary care setting increases the knowledge of people with chronic obstructive pulmonary disease: A randomized controlled trial. Patient Education and Counseling. 81:14-18. 2010
- Etiology of troponin elevation in critically ill patients. Journal of Critical Care. 25:322-328. 2010
- Prevalence and underdiagnosis of chronic obstructive pulmonary disease among patients at risk in primary care. CANADIAN MEDICAL ASSOCIATION JOURNAL. 182:673-678. 2010
- Stopping Randomized Trials Early for Benefit and Estimation of Treatment Effects<subtitle>Systematic Review and Meta-regression Analysis</subtitle>. Journal of the American Medical Association (JAMA). 303:1180-1180. 2010
- Use of both short musculoskeletal function assessment questionnaire and short form-36 among tibial-fracture patients was redundant. Journal of Clinical Epidemiology. 62:1210-1217. 2009
- Is a Pre-Operative Brain Natriuretic Peptide or N-Terminal Pro–B-Type Natriuretic Peptide Measurement an Independent Predictor of Adverse Cardiovascular Outcomes Within 30 Days of Noncardiac Surgery?. Journal of the American College of Cardiology. 54:1599-1606. 2009
- The diagnosis of myocardial infarction in critically ill patients: An agreement study. Journal of Critical Care. 24:447-452. 2009
- Interobserver Reliability of Classification Systems to Rate the Quality of Femoral Neck Fracture Reduction. Journal of Orthopaedic Trauma. 23:408-412. 2009
- Radiographs of hip fractures were digitally altered to mask surgeons to the type of implant without compromising the reliability of quality ratings or making the rating process more difficult. Journal of Clinical Epidemiology. 62:214-223.e1. 2009
- Specific HRQL instruments and symptom scores were more responsive than preference-based generic instruments in patients with GERD. Journal of Clinical Epidemiology. 62:102-110. 2009
- Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2). Trials. 10:49-49. 2009
- Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials. Trials. 10:101-101. 2009
- Hand hygiene in the intensive care unit: prospective observations of clinical practice. Polskie Archiwum Medycyny Wewnetrznej. 118:543-547. 2008
- Prophylaxis Against Deep Vein Thrombosis in Critically Ill Patients With Severe Renal Insufficiency With the Low-Molecular-Weight Heparin Dalteparin<subtitle>An Assessment of Safety and Pharmacodynamics: The DIRECT Study</subtitle>. JAMA Internal Medicine. 168:1805-1805. 2008
- Enrollment of intensive care unit patients into clinical studies: A trinational survey of researchersʼ experiences, beliefs, and practices*. Critical Care Medicine. 36:2100-2105. 2008
- Author reply: the master-question: meta-analyses and stopped-early randomized trials—a problem?. Journal of Clinical Epidemiology. 61:96-98. 2008
- Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin prophylaxis: prevalence, incidence and risk factors. Critical Care. 12:R32-R32. 2008
- Application of generalizability theory confirmed lower reliability of the standard gamble than the feeling thermometer. Journal of Clinical Epidemiology. 60:1256-1262. 2007
- Systematic reviewers neglect bias that results from trials stopped early for benefit. Journal of Clinical Epidemiology. 60:869-873. 2007
- Lowering of Glucose in Critical care: a randomized pilot trial. Journal of Critical Care. 22:112-118. 2007
- A randomized trial of Pegaptanib sodium for age-related macular degeneration used an innovative design to explore disease-modifying effects. Journal of Clinical Epidemiology. 60:456-460. 2007
- Bleeding during critical illness: A prospective cohort study using a new measurement tool. Clinical and Investigative Medicine. 30:93-93. 2007
- Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. The BMJ. 334:786-786. 2007
- The Work Productivity and Activity Impairment Questionnaire for Patients with Gastroesophageal Reflux Disease (WPAI-GERD). PharmacoEconomics (Auckland). 25:385-396. 2007
- Elevated Cardiac Troponin Measurements in Critically Ill Patients. JAMA Internal Medicine. 166:2446-2446. 2006
- Meta-analysis of flavonoids for the treatment of haemorrhoids. British Journal of Surgery. 93:909-920. 2006
- Reliability of electrocardiogram interpretation in critically ill patients. Critical Care Medicine. 34:1338-1343. 2006
- Reliability of electrocardiogram interpretation in critically ill patients*. Critical Care Medicine. 34:1338-1343. 2006
- Validation of a symptom diary for patients with gastro‐oesophageal reflux disease. Alimentary Pharmacology and Therapeutics. 23:531-541. 2006
- Fiber for the Treatment of Hemorrhoids Complications: A Systematic Review and Meta-Analysis. American Journal of Gastroenterology. 101:181-188. 2006
- Fiber for the treatment of hemorrhoids complications:: A systematic review and meta-analysis. American Journal of Gastroenterology. 101:181-188. 2006
- Is blinding the endoscopists to bowel preparations in randomized-controlled trials a reality?. Cancer Epidemiology. 30:552-559. 2006
- Internal consistency reliability is a poor predictor of responsiveness. Health and Quality of Life Outcomes. 3:33. 2005
- The impact of illness in patients with moderate to severe gastro-esophageal reflux disease. BMC Gastroenterology. 5:23. 2005
- Laxatives for the treatment of hemorrhoids.. Cochrane Database of Systematic Reviews. 2010:CD004649. 2005
- A Randomized Trial of Strategies for Assessing Eligibility for Long-Term Domiciliary Oxygen Therapy. American Journal of Respiratory and Critical Care Medicine. 172:573-580. 2005
- A randomized trial of strategies for assessing eligibility for long-term domiciliary oxygen therapy. American Journal of Respiratory and Critical Care Medicine. 172:573-580. 2005
- The effect of bright light therapy on depression associated with premenstrual dysphoric disorder. American Journal of Obstetrics and Gynecology. 193:658-661. 2005
- An analysis of general medical and specialist journals that endorse CONSORT found that reporting was not enforced consistently. Journal of Clinical Epidemiology. 58:662-667. 2005
- Bilevel noninvasive positive pressure ventilation for acute respiratory failure: Survey of Ontario practice*. Critical Care Medicine. 33:1477-1483. 2005
- Capability of ischemia-modified albumin to predict serious cardiac outcomes in the short term among patients with potential acute coronary syndrome. CANADIAN MEDICAL ASSOCIATION JOURNAL. 172:1685-1690. 2005
- Elevated troponin and myocardial infarction in the intensive care unit: a prospective study.. Critical Care. 9:R636-R636. 2005
- The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole.. Health and Quality of Life Outcomes. 3:4-4. 2005
- An observational study found that authors of randomized controlled trials frequently use concealment of randomization and blinding, despite the failure to report these methods. Journal of Clinical Epidemiology. 57:1232-1236. 2004
- A Randomized Multicenter Trial to Evaluate Simple Utility Elicitation Techniques in Patients With Gastroesophageal Reflux Disease. Medical Care. 42:1132-1142. 2004
- Do physicians correctly assess patient symptom severity in gastro‐oesophageal reflux disease?. Alimentary Pharmacology and Therapeutics. 20:1161-1169. 2004
- Payments for care at private for-profit and private not-for-profit hospitals: a systematic review and meta-analysis. CANADIAN MEDICAL ASSOCIATION JOURNAL. 170:1817-1824. 2004
- Association between industry funding and statistically significant pro-industry findings in medical and surgical randomized trials.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 170:477-480. 2004