Active Grants for the Health Research Methods, Evidence, and Impact department

Grant Name Close Date
10-year Follow-Up of the South Asian Birth Cohort: Understanding early life determinants of cardiovascular disease 9/30/2026
A Clinical Prediction Model for the Diagnosis of Immune Thrombocytopenia 9/30/2025
A Community Based Research Project: Analyzing The Barriers And Facilitators To Healthy Active Living Amongst Newly Immigrated Families With Children 4/30/2025
A Phase 3 Prospective, Randomized, Partially Blinded Multi-Center Study to Measure the Safety and Efficacy of NOVOCART 3D Compared to Microfracture in the Treatment of Articular Cartilage Defects 1/1/2025
A Phase I Qualitative Study to Develop a New Patient-Reported Outcome Instrument for Children with Congenital and Acquired Differences of the Hands and Upper Limb 4/30/2026
A Phase III Non-Inferiority Randomized Controlled Trial (RCT) of Fixed-Duration Daratumumab Versus Continuous Daratumumab Among Transplant Ineligible Older Adults with Newly-Diagnosed Multiple Myeloma 10/31/2031
A ProSpective, MulticEnter, Concurrently Controlled Clinical Study of Chondro-GideĀ® ArticUlar Cartilage CoveR for the Treatment of Large Chondral Lesions in the KnEe (SECURE) 1/1/2026
A Randomized Trial of Partial Breast Irradiation 9/30/2028
A Randomized Trial of Regional Radiotherapy in Luminal A Breast Cancer 6/30/2025
A Single Dose Antenatal Corticosteroids (SNACS) Non-Inferiority Randomized Control Trial for Pregnancies at Risk of Preterm Delivery 5/31/2029
A phase 2 trial to evaluate safety and immunogenicity of a next-generation COVID-19 vaccine delivered by inhaled aerosol to humans 8/31/2025
A phase 2 trial to evaluate safety and immunogenicity of a next-generation COVID-19 vaccine delivered by inhaled aerosol to humans 8/31/2025
Accelerating Clinical Trials (ACT) - Canada 8/31/2025
Accelerating Clinical Trials (ACT) - Canada 8/31/2025
Addressing cardiovascular co-morbidities in patients with cancer (C3) 11/30/2024
Advancing equity in maternal and perinatal care in Canada: Population-based investigations of racial and ethnic disparities in severe maternal morbidity and severe perinatal morbidity and mortality 3/31/2027
Aldosterone blockade for Health Improvement Evaluation in End-stage kidney disease: Extension 9/30/2027
An International Multiphase Program of Research to Develop and Implement a Patient-Reported Outcome Measure for Gender-Affirming Treatments (GENDER-Q) 6/30/2026
An innovative technology-based approach to translating clinical practice guidelines of nutrition therapy in primary care: The Cost, Health, and Effectiveness Assessment of the Portfolio diet in Primary care (CHEAPP) program 3/31/2027
An innovative technology-based approach to translating clinical practice guidelines of nutrition therapy in primary care: The Cost, Health, and Effectiveness Assessment of the Portfolio diet in Primary care (CHEAPP) program 3/31/2027
Anticoagulation for stroke prevention in patients with recent episodes of perioperative atrial fibrillation after noncardiac surgery - The ASPIRE-AF study 9/30/2026
Assessing the utility of a new class of inheritance mediated by a rare variant genetic risk score for chronic disease prediction 4/30/2025
Association of socioeconomic and environmental factors with neonatal and childhood outcomes of preterm neonates <29 weeks' gestation in Canada 3/31/2025
Autologous MatRix-Induced ChondrogenEsis ComPared with Microfracture for Focal ArtIcular CaRtilage Damage of the Hip (REPAIR): A Pilot Randomized Controlled Trial 12/31/2026
Autologous MatRix-Induced ChondrogenEsis ComPared with Microfracture for Focal ArtIcular CaRtilage Damage of the Hip (REPAIR): A Pilot Randomized Controlled Trial 12/31/2026
Autologous MatRix-Induced ChondrogenEsis ComPared with Microfracture for Focal ArtIcular CaRtilage Damage of the Hip (REPAIR): A Pilot Randomized Controlled Trial 12/31/2026
Autologous MatRix-Induced ChondrogenEsis ComPared with Microfracture for Focal ArtIcular CaRtilage Damage of the Hip (REPAIR): A Pilot Randomized Controlled Trial 12/31/2026
Avoiding Diabetes After Pregnancy Together with Moms (ADAPT-M): Bridging care between the third and fourth trimester 3/31/2028
Bariatric surgery for the Reduction of cArdioVascular Events randomized controlled (BRAVE) trial: vanguard phase for assessment of feasibility 9/30/2025
Building system capacity for home visits for patients near the end of life: A mixed methods study 3/31/2026
CLEAR trial: A 2 x 2 factorial randomized trial of CoLchicine and spironolactonE in patients with myocARdial infarction. 3/31/2026
COLchicine in Ischemic Heart Failure (COL-IHF) 3/31/2027
COMPLETE-2: A prospective, randomized, multi-centre trial of physiology-guided versus angiography-guided complete revascularization to treat multivessel disease after early percutaneous coronary intervention for ST-segment elevation myocardial infarction. 9/30/2025
Canada Reseach Chair - Tier 1 12/31/2028
Canada Reseach Chair - Tier 1 12/31/2028
Canada Research Chair - Tier 1 3/31/2025
Canada Research Chair - Tier 2 1/31/2025
Canada Research Chair - Tier 2 1/31/2025
Canada Research Chair - Tier 2 3/31/2026
Canada Research Chair - Tier 2 3/31/2026
Canada Research Chair - Tier 2 3/31/2027
Canada Research Chairs - Tier 2 8/31/2025
Canadian Alliance of Healthy Hearts and Minds: Dissecting the Pathways Linking Ectopic Adipose Tissue to Cognitive Dysfunction 9/30/2028
Canadian Cancer Rehabilitation (CanRehab) Team: Improving the systematic identification, management, and treatment of the adverse effects of cancer. 11/30/2024
Canadian Heart Failure Transformation Alliance: A Network of Likeminded Canadians Committed to Improving the Lives of Persons Living with Heart Failure (HF) 4/30/2027
Canadian Network for Statistical Training in Trials (CANSTAT) 8/31/2025
Canadian Network for Statistical Training in Trials (CANSTAT) 8/31/2025
Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis. 11/30/2024
Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis. 11/30/2024
Chronic Pain Network: Moving towards knowledge mobilization and implementation science 3/31/2026
Chronic diseases in mothers and risks of neuro-developmental disorders in offspring: an international comparison 9/30/2024
Cigarette taxes, prices and tax evasion in Canada: implications for tobacco control 9/30/2024
Deriving 24-hour Ambulatory Blood Pressure Monitoring reference values for SouTh AsiaN Children (ABPM-STANCE) 9/30/2026
Development and testing of the McMaster Cough Severity Questionnaire: a new cough symptom severity instrument for patients with chronic cough 4/30/2025
Early arthroscoPic stabilization veRsus rehabilitatiOn of the shoulder in adolescents with a trauMatic first-time anterior shoulder dislocation ePisode: A Randomized Controlled Trial (PROMPT) 12/31/2025
EnVISION No Pain After Surgery: A Pilot Study of Automated Pain Assessments Following Surgery to Help Prevent Chronic Post-Surgical Pain 4/30/2025
Enhancing a Community of Practice for the Health System Impact Fellowship Program: Advancing Capacity for Sustainable & Patient-Centred Learning Health Systems across Canada 12/31/2024
Establishing evidence-based strategic recommendations for patient-centred health care options for individuals experiencing high use of the emergency department 12/31/2024
Estimating the number of children who experience parental incarceration and describing their health status using linked whole population data for five Canadian provinces: The CHIRP (Children with IncarceRated Parents) Study. 3/31/2025
Evaluating the palliative and end-of-life care of older Canadians living and dying with dementia 9/30/2024
Examining the Impacts of the COVID-19 Pandemic Response on Health and Functioning of Canadian Children and Youth 9/30/2025
Expanding midwifery services in Canada: Improving equitable access to sexual and reproductive healthcare through midwifery contributions 3/31/2026
FetAS: Fetal Assessment Suite to Facilitate Rapid Fetal MRI Diagnosis using Artificial Intelligence 9/30/2028
Further Refinement and Multi-country Validation of a Preliminary Set of Quality Indicators for Palliative Care 3/31/2025
Getting Fit for Hip or Knee Replacement: The Fit Joints Randomized Controlled Trial of A Multimodal Intervention in Frail Patients with Osteoarthritis 3/31/2025
Guideline for cannabis use in chronic pain 12/31/2024
HIP fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) trial - 2 9/30/2024
HIP fracture Accelerated surgical TreaTment And Care tracK-2 (HIP ATTACK-2) trial 7/31/2026
Health and neurodevelopmental trajectories of children and adolescents born at preterm and term gestation 9/30/2027
IMAGINE (Inflammation, Microbiome, and Alimentation: Gastro-Intestinal and Neuropsychiatric Effects) SPOR Chronic Disease Network - Knowledge Mobilization & Implementation Science Phase 2 3/31/2026
Improving Maternity Outcomes by Engaging Stakeholders in a Holistic Assessment of the Social and Clinical Determinants of Severe Maternal Morbidity in Canada - a Feasibility Study 9/30/2024
InnoVatiOn for Indigenous-led dementia Care to Enhance Safety (VOICES) 9/30/2027
Intergenerational impacts of diabetes among First Nations mothers and their children 9/30/2025
Intravenous Ketorolac versus Morphine in Children Presenting with Suspected Appendicitis: A Multi-Centre Non-Inferiority Randomized Controlled Trial 9/30/2027
Kaiso, Triple Negative Breast Cancer and Women of African Ancestry. 9/30/2025
Kidney and blood pressure disease burden and monitoring for chronic kidney disease in childhood cancer survivors 3/31/2026
Large-scale computer-based retinal image analyses combined with genetic and blood biomarker association studies to identify new therapeutic targets for prevention of cardiovascular diseases 9/30/2024
Long COVID Web: Pan-Canadian Post-COVID Condition Research Network 10/31/2027
Long-term results of the LUMINA prospective cohort study evaluating the risk of local recurrence in low Risk luminal a breast cancer 12/31/2024
Longitudinal effects of cannabis legalization in a community cohort of Canadian adults 9/30/2025
Low dose ColchicinE in pAtients with peripheral artery DiseasE to address residual vascular Risk (LEADER-PAD): A multinational randomized trial 9/30/2028
Mobilizing Knowledge and Implementing Equitable and Cost-Effective Health and Social Care Services for Persons Living with Diabetes in Canada 3/31/2026
Multimodal opioid-sparing postoperative pain protocol versus standard of care for patients undergoing knee and shoulder arthroscopy: a randomized controlled trial and knowledge translation strategy 6/30/2024
Multimodal opioid-sparing postoperative pain protocol versus standard of care for patients undergoing knee and shoulder arthroscopy: a randomized controlled trial and knowledge translation strategy 6/30/2024
Ontario SPOR SUPPORT Unit: Ontario's Catalyst for Patient-Oriented Research 3/31/2026
Optimizing Fracture Clinics by Having Social Workers Provide Mental Health Support to Fracture Patients. 6/1/2024
PRECEDE: Preconception risk factors and Cardiometabolic health in Early childhood 3/31/2025
Pediatric Autism Research Cohort (PARC): A patient-oriented prospective study examining trajectories of functioning in Canadian children with Autism 9/30/2027
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual), a simple perioperative anticoagulant management approach, replacing a resource-intensive in-person doctor-patient consultation, with a simple virtual care model that will provide a new standard of care for patients on a Direct Oral Anticoagulant or warfarin and require elective surgery/procedure. 9/30/2024
Post-Operative Functional Recovery in Patients with FAI 7/31/2024
Pregnant during the COVID-19 pandemic: A prospective, multi-method study examining the impact of chronic prenatal stress on child outcomes. 9/30/2025
Preventing Vision Loss from Diabetic Retinopathy: Guiding Primary Care Diabetic Retinopathy Screening in Canada Through the Use of Provincial Healthcare Administrative Data 12/31/2026
Prevention of persistent pain with LidocAine iNfusions in breast cancer surgery (PLAN): a multicentre randomized controlled trial 9/30/2024
Prospective Evaluation of Breast-Conserving Surgery Alone in Low Risk Ductal Carcinoma in Situ Defined by a Molecular Expression Assay Combined with Clinico-Pathological Features 9/30/2026
Prospective Evaluation of Sports Activity and the Development of Femoroacetabular Impingement in the Adolescent Hip (PREVIEW) 8/31/2025
Prospective, multicentre, randomized, parallel-control, superiority study comparing administration of clotting factor concentrates with a standard massive hemorrhage protocol in severely bleeding trauma patients 9/30/2024
REsponSiveness of urEmic sympToms to DIALYSIS (RESET-DIALYSIS) 9/30/2024
RYR2-targeted Gene Therapies for Treating Catecholaminergic Polymorphic Ventricular Tachycardia 9/30/2027
Retaining and Attracting Workers in Long-Term Care Homes: How System Dynamics Can Help 9/30/2024
Risk prediction of heart failure using an integrated genomic-proteomic approach 9/30/2024
SMILE: Optimising SMarter Inclusive Living Environments for ageing people within their circles of care. 12/31/2024
SPOR National Data Platform 8/31/2025
Safety and Efficacy of NOVOCARTĀ® 3D in the Treatment of Articular Cartilage Defects following failure on Microfracture (RESCUE) 1/1/2028
Salary Support Award for Dr. Greg Pond 3/31/2025
Scaling up shared decision making for patient-centred care 6/30/2025
Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients: START-POAF Pilot Trial 3/31/2025
Sleep, Circadian Rhythms, and Dementia-Related Changes in the Human Brain - An Integrated Physiological, Magnetic Resonance Imaging, Cognitive, and Genomic Study of Adult Ontarians 9/30/2025
Small Steps for Big Changes: Implementing an Evidence-Based Diabetes Prevention Program into Diverse Urban Communities 9/30/2028
Soft-tissue QUadriceps autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings (SQUASH): A Multi-Centre Pilot Randomized Controlled Trial 12/31/2025
Soft-tissue QUadriceps autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings (SQUASH): A Multi-Centre Pilot Randomized Controlled Trial 12/31/2025
Stakeholder engagement in health care systematic reviews 9/30/2025
Stress Ulcer Prophylaxis in the Critically Ill; REVISE Renewal Grant 8/31/2024
Stress Ulcer Prophylaxis in the Critically Ill; REVISE Renewal Grant 8/31/2024
Synthesizing evidence to inform decision-making in the context of a pandemic: balancing efficiency with methodological rigour 9/30/2024
Targeted Therapy with Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Right Ventricular Cardiomyopathy (TARGETED-ARVC) 8/31/2025
Targeted Therapy with Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Right Ventricular Cardiomyopathy (TARGETED-ARVC) 8/31/2025
Targeting immunodominant regions on platelet factor 4 for the diagnosis and treatment of heparin-induced thrombocytopenia 9/30/2025
The "Atrial FIBrillation in Pregnancy: assessing seveRe matErnal morbidity and anticoagulation strateGies" (AFIB-PREG) Study 9/30/2024
The "predicting Short-term Adverse cardiovasculaR outcomes in preeclampsiA using BIomarkers" (SARABI) Pilot Study 9/30/2025
The CYCLE research program: Teamwork excellence to inform an international randomized clinical trial of early rehabilitation using cycle ergometry in mechanically ventilated patients 6/30/2024
The Canadian CABG or PCI in Patients with Ischemic Cardiomyopathy (STICH 3.0) Trial 3/31/2029
The Canadian Collaboration for Complex Care: Innovations for optimal and appropriate care for all 7/31/2025
The Effect of Canadian Income Transfer Programs on Health 9/30/2027
The TACtful Trial: A first-in-human multi-centre trial of BCMA specific T-cell antigen coupler infusion, generated from cryopreserved G-CSF-mobilized peripheral blood, in patients with relapsed and refractory multiple myeloma. 9/30/2028
The efficacy of soluble, dietary fibre supplementation for the treatment of paediatric non-alcoholic fatty liver disease (NAFLD). 3/31/2027
The impact of cannabis smoke on respiratory tract viral infections 3/31/2028
The impact of opioid and cannabis use during pregnancy on placental and fetal development 9/30/2027
Therapeutic Plasma Exchange in Septic Shock (PLEXSIS): A Pilot Study 3/31/2026
Training Intervention and Program of Support (TIPS) for fostering the adoption of family-centred telehealth interventions in pediatric rehabilitation: A pan-Canadian implementation-effectiveness study. 9/30/2025
Understanding the impact of the COVID-19 pandemic on obesity and diabetes among Canadians; a prospective population-based cohort study 9/30/2026
Understanding the intersection of frailty, sepsis, and cancer: Rehabilitation to improve survivor outcomes (the I-CaRe project) 6/1/2024
University Scholar 6/30/2026
Urinary Biomarkers of Tobacco Smoke Exposure and Harm: An Exposomics Approach to Understand the Smoking Paradox 3/31/2026
Using the Robson classification system to examine maternal and perinatal safety associated with operative delivery options in the second stage of labour 4/30/2026
Validation of a novel biomarker classifier that predicts radiation response following breast-conserving surgery for ductal carcinoma in situ (DCIS) 3/31/2027
Vascular events in patients undergoing same-day noncardiac surgery (VALIANCE) - a prospective cohort and nested biobank study 3/31/2026
iCARE 2.0 -Biopsychosocial risk factors for kidney disease in youth onset type 2 diabetes; Longitudinal evaluation and Pilot study of a novel skills-based mental health intervention 3/31/2026