Active Grants for the Biochemistry & Biomedical Sciences department

Grant Name Close Date
A Tale of Two Receptors: Antibiotics Bypassing the Outer Membrane 4/30/2024
A lactate trap that lowers blood glucose and liver fat 3/31/2026
A pilot randomized, double-placebo controlled trial of sublingual or oral immunotherapy for tree nut allergy (TRADE) 9/30/2027
A postbiotic approach that improves metabolic disease 4/30/2025
A quantitative look at protein diffusion in cells and crowded media 3/31/2025
Accelerating Clinical Trials (ACT) - Canada 8/31/2025
Accelerating Clinical Trials (ACT) - Canada 8/31/2025
Additive Manufacturing of customized imaging instrumentation for SARS- CoV-2 viral research 6/30/2024
Adverse outcomes of aged mice are associated with adipose tissue failure after burn 5/31/2028
Assessing the utility of a new class of inheritance mediated by a rare variant genetic risk score for chronic disease prediction 4/30/2025
Bariatric surgery for the Reduction of cArdioVascular Events randomized controlled (BRAVE) trial: vanguard phase for assessment of feasibility 9/30/2025
Beneficial microbes to prevent neonatal GBS disease 8/31/2026
Burn induces hypermetabolism via browning of the white adipose tissue 4/30/2025
Canada Research Chair - Tier 1 6/30/2024
Canada Research Chair - Tier 1 6/30/2024
Canada Research Chair - Tier 1 9/30/2024
Canada Research Chair - Tier 1 9/30/2024
Canada Research Chair - Tier 1 9/30/2028
Canada Research Chair - Tier 1 3/31/2029
Canada Research Chair - Tier 1 - CIHR Funded 6/30/2025
Canada Research Chair - Tier 1 - CIHR Funded 6/30/2025
Canada Research Chair - Tier 2 6/30/2027
Canadian Alliance of Healthy Hearts and Minds: Dissecting the Pathways Linking Ectopic Adipose Tissue to Cognitive Dysfunction 9/30/2028
Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis. 11/30/2024
Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis. 11/30/2024
Cannabis exposure in utero: impact on the developmental programming of the gut-brain axis 9/30/2028
Causational Roles of the Gut Microbiome in Childhood Asthma: Leveraging the CHILD Cohort Study 10/31/2024
Clinical development of oncolytic BHV-1 for cancer therapy 9/30/2024
Deciphering the metabolic reprogramming of medulloblastoma: novel therapeutic targets and liquid biopsy biomarkers 4/30/2026
Development of AML-Relapse Therapeutics (DART) 1/27/2025
Development of a Personalized Epigenetic Maintenance Approach for AML and MDS Patients after Allogeneic Stem Cell Transplantation 9/30/2024
Development of a Personalized Epigenetic Maintenance Approach for AML and MDS Patients after Allogeneic Stem Cell Transplantation 12/31/2024
Dietary drivers of proinflammatory bacterial proteolytic activity in colitis. 9/30/2027
Dissecting host-microbiome modifiers of type 2 diabetes risk 10/31/2024
Dynamic Nanoimaging of DNA Damage and Repair in Neurodegenerative Diseases. 11/11/2025
Dynamic metabolic reprogramming drives myc-amplified medulloblastoma recurrence 3/31/2028
Elucidating the molecular mechanism by which bat Interferon Regulatory Factors modulate antiviral responses 9/30/2024
Elucidation of the Vaginal Microbiome to Assess HIV Susceptibility: A Multi-Omics Approach 6/30/2024
Energy Sensing and Metabolism: From Mechanisms to New Therapies 6/30/2025
Engineering solid tumors for bispecific immunotherapies through controlled delivery 9/30/2026
Exploring new growth modes and developmental trajectories for Streptomyces bacteria 4/30/2025
Generating an Off the Shelf T-Cell Therapy Using Covalent Immune Recruiters 4/30/2026
Genetic basis of host adaptability and biogeography of adherent-invasive Escherichia coli 3/31/2027
Grappling with type IV pili: characterization of Nature's most powerful biological motor 3/31/2025
Healthy Life Trajectories Initiative (HeLTI) - South Africa - Bukhali 1/31/2027
Host iNOS dictates gut dysbiosis, bacterial translocation and tissue insulin resistance in murine and human obesity 6/30/2027
IMAGINE (Inflammation, Microbiome, and Alimentation: Gastro-Intestinal and Neuropsychiatric Effects) SPOR Chronic Disease Network - Knowledge Mobilization & Implementation Science Phase 2 3/31/2026
Immunogenic wheat protein metabolism by gut bacteria. 3/31/2025
Investigating The Role of Serotonin in The Development of Non-Alcoholic Steatohepatitis 3/31/2025
Investigating the Influence of the Human Gut Microbiota in Parkinson's Disease 4/30/2024
It takes two to tango: Parental obesity and sex-specific impacts on placental development 3/31/2026
Land-Based Community Monitoring of Selenium in the Canadian Rockies: Stoney Nakoda Women's Health and Well-Being 3/31/2027
Large-scale computer-based retinal image analyses combined with genetic and blood biomarker association studies to identify new therapeutic targets for prevention of cardiovascular diseases 9/30/2024
Macrophage Covalent Immune Recruiters (mCIRs): A novel synthetic immunotherapeutic enforcing tumor immune recognition 12/31/2025
Mechanisms of weight loss due to dual GIP GLP-1 receptor agonism with tirzepatide compared to semaglutide 9/30/2028
Metabolic targeting of AML cells in their microenvironment 6/30/2025
Metformin administration restores depleted NAD levels to improve outcomes in elderly burn patients 4/30/2025
Minimal Residual Disease (MRD) Research Laboratory to Target Acute Myeloid Leukemia 11/11/2025
Modelling the earliest stages of cellular life 3/31/2028
Molecular Targeting of Human Acute Myeloid Leukemia and Bone Marrow Regeneration 6/30/2025
Moving beyond blood glucose with continuous multiplexed hormone measurement 9/30/2026
Optical Imaging in the Pre-Clinical Setting 11/11/2025
Pregnant during the COVID-19 pandemic: A prospective, multi-method study examining the impact of chronic prenatal stress on child outcomes. 9/30/2025
REsponSiveness of urEmic sympToms to DIALYSIS (RESET-DIALYSIS) 9/30/2024
RYR2-targeted Gene Therapies for Treating Catecholaminergic Polymorphic Ventricular Tachycardia 9/30/2027
Randomized Clinical Trial of Propranolol in Severely Burn Patients 6/30/2024
Regulatory solutions to the antibiotic production challenge 3/2/2029
Resolving complex outcomes in 15q13.3 copy number variants using emerging diagnostic and biomarker tools 12/31/2025
Risk prediction of heart failure using an integrated genomic-proteomic approach 9/30/2024
Role of microbes in the pathogenesis of PIBD: From discovery, through causation, to novel treatments 10/31/2024
STARS: Surveillance and Testing for Antiviral Resistance in SARS-CoV-2 9/30/2024
Sleep, Circadian Rhythms, and Dementia-Related Changes in the Human Brain - An Integrated Physiological, Magnetic Resonance Imaging, Cognitive, and Genomic Study of Adult Ontarians 9/30/2025
Stem cell models to investigate brain function in development and disease 12/16/2026
Targeting Sensory Dysfunctions in Autism Spectrum Disorders 11/30/2024
Targeting immunodominant regions on platelet factor 4 for the diagnosis and treatment of heparin-induced thrombocytopenia 9/30/2025
Targeting responsive microenvironment to prevent relapse of human acute myeloid leukemia 1/31/2025
The TACtful Trial: A first-in-human multi-centre trial of BCMA specific T-cell antigen coupler infusion, generated from cryopreserved G-CSF-mobilized peripheral blood, in patients with relapsed and refractory multiple myeloma. 9/30/2028
The adverse impact of prenatal cannabinoid exposure on placental and postnatal cardiovascular function: can we intervene? 9/30/2027
The efficacy of soluble, dietary fibre supplementation for the treatment of paediatric non-alcoholic fatty liver disease (NAFLD). 3/31/2027
The impact of cannabis smoke on respiratory tract viral infections 3/31/2028
The mechanisms underlying signaling by the HDL-receptor SR-B1 in myeloid cells and role in protection against coronary artery atherosclerosis 9/30/2026
The role of microbial bioactive lipids in pain signaling and colitis 12/31/2024
Therapeutic targeting of Purine metabolism in Brain metastases 9/30/2027
Therapeutics for CF Pathogens 3/3/2025
Training Researchers In the Next generation in Gastroenterology and Liver (TRIANGLE) 12/31/2027
Training platform in diabetes, obesity and cardiometabolic health 12/31/2027
Uncovering the role of the gut microbiome in unhealthy aging and frailty 3/31/2028
Understanding susceptibility and permissiveness to mpox virus across diverse mammalian species 2/28/2025
Urinary Biomarkers of Tobacco Smoke Exposure and Harm: An Exposomics Approach to Understand the Smoking Paradox 3/31/2026
Vascular events in patients undergoing same-day noncardiac surgery (VALIANCE) - a prospective cohort and nested biobank study 3/31/2026