Characteristics of Pediatric Patients With Celiac Disease Identified Due to an Affected First‐Degree Family Member

The incidence of celiac disease in first‐degree relatives of affected individuals is higher than in the general population, yet the clinical characteristics of this unique subset of patients has not been well described. Through a retrospective review of patients seen in a tertiary care pediatric celiac disease clinic, we identified 49 patients diagnosed with celiac disease following screening due to an affected first‐degree relative. Although 51% of patients screened due to an affected first‐degree relative were asymptomatic, their disease histology was as severe as those screened for symptoms suggestive of celiac disease. These findings support current recommendations to screen all first‐degree relatives of patients with celiac disease regardless of clinical symptoms.

Characteristics of Pediatric Patients With Celiac Disease Identified Due to an Affected First‐Degree Family Member Journal Articles