Future Trends in Antimicrobial Chemotherapy: Expert Opinion on the 43^rdICAAC Conferences

abstract

• The current document bestows an expert synopsis of key new information presented at the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) meeting in 2003. Data is presented on the socio-political aspects of and policies on antimicrobial prescribing, novel mechanisms of resistance in Streptococcus pneumoniae, and current epidemiological trends in global resistance. Novel information on new (and existing) antimicrobial agents--new penicillins, cephalosporins, monobactams and oxipenem inhibitors, ketolides, glycopeptides, fluoroquinolones (and hybrids), peptides, daptomycin, aminomethylcyclines, glycylcyclines, and newer formulations of agents such as amoxycillin-clavulanate--provides renewed hope that resistant pathogens can be controlled through use of more potent agents. Improved strategies for the use of existing antimicrobial agents, such as the use of high-dose regimens, short-course therapy, also may delay or reduce the development of resistance and preserve the value of our antibiotic armamentarium.

authors

• Ball, AP
• Bartlett, JG
• Craig, WA
• Drusano, GL
• Felmingham, D
• Garau, JA
• Klugman, KP
• Low, DE
• Mandell, Lionel
• Rubinstein, E
• Tillotson, GS

status

• published 

publication date

• October 2004

has subject area

• 1115 Pharmacology and Pharmaceutical Sciences (FoR)
• Anti-Bacterial Agents (MeSH)
• Congresses as Topic (MeSH)
• Drug Resistance, Bacterial (MeSH)
• Humans (MeSH)
• Microbiology (Science Metrix)
• Practice Guidelines as Topic (MeSH)
• Practice Patterns, Physicians' (MeSH)
• Streptococcus pneumoniae (MeSH)

published in

• Journal of Chemotherapy  Journal

keywords

• Anti-Bacterial Agents
• Congresses as Topic
• Drug Resistance, Bacterial
• Humans
• Practice Guidelines as Topic
• Practice Patterns, Physicians'
• Streptococcus pneumoniae

Digital Object Identifier (DOI)

• 10.1179/joc.2004.16.5.419

PubMed ID

• 15565907

start page

• 419

end page

• 436

volume

• 16

issue

• 5